Table 1.

Properties of MAbs

MAbIgG isotypeProtectionImmunoprecipitationImmunoblottingIFAaCross-reaction with PfAMA-1
60-kDa AMA-1140-kDa speciesAMA-1140-kDa speciesFixedUnfixed
−DTT+DTT−DTT+DTT
8D22bNDb ND+A/CNDND
42A51NDNDNDNDNDNDA/CNDND
45B12a++±+A/CA/C
45D112bNDNDNDNDNDNDA/CNDND
47B42aNDNDNDNDNDNDA/CNDND
48B21++++++A/C+
48F81+++AA/C
28G2dc1c ND+++A/C+
58F8dc1c NDNDND+
  • a A, apical fluorescence; C, circumferential (merozoite surface).

  • b ND, not done.

  • c Previously reported (32).