TABLE 1

Enriched gene ontology biological processes in persistent- versus transient-infection MPEC strains based on differentially expressed genes

Gene group and GO termNo. of genesP valueGene names
Genes with higher expression in persistent-infection isolates
    Bacterial-type flagellum-dependent cell motility151.10E−13fliF, fliE, flgK, flgL, fliK, fliG, fliM, fliN, fliS, fliJ, flgJ, fliI, fliH, flgI, fliT
    Lipopolysaccharide biosynthetic process152.10E−10arnT, wzzE, wcaH, wecA, wcaK, wcaM, arnA, eptA, wcaI, wcaL, wcaN, wzzB, arnC, arnD, arnB
    Bacterial-type flagellum assembly97.10E−09flgN, fliQ, flhD, flgK, fliK, fliG, fliS, flgJ, fliI
    Bacterial-type flagellum organization72.50E−07flgM, fliO, fliP, flhC, fliJ, fliH, fliT
    Iron ion homeostasis71.10E−04fecI, fecA, fecR, fecE, fecB, fecC, fecD
    Chemotaxis66.80E−04dppA, fliO, fliG, fliN, fliJ, trg
    Response to iron(III) ion47.00E−04arnT, basR, basS, arnD
    Lipid A biosynthetic process68.40E−04arnT, arnA, eptA, arnC, arnD, arnB
    Slime layer polysaccharide biosynthetic process43.80E−03wcaK, wcaM, wcaI, wcaL
    Ion transport63.90E−03fecI, fecR, fecE, fecB, fecC, fecD
    Gamma-aminobutyric acid catabolic process31.10E−02gabT, gabP, gabD
    Cell adhesion52.40E−02fimI, fimD, fimF
Genes with higher expression in transient-infection isolates
    Mo-molybdopterin cofactor biosynthetic process48.20E−03moaB, moaC, moaE, moaD
    Molybdopterin cofactor biosynthetic process31.50E−02moaB, moaC, moaE