Table 2.

Self-reported symptoms during 4 days after the first and second doses of oral ETEC vaccine (lot E005) or placebo

SymptomNo. (%) reported
Dose 1Dose 2
Placebo (n = 45)Vaccine (n = 45)Placebo (n = 41)Vaccine (n = 37)
Any21 (47)30 (67)16 (39)12 (32)
Diarrhea2 (4)0 (0)0 (0)0 (0)
Fever0 (0)0 (0)0 (0)0 (0)
Abdominal cramps8 (18)15 (33)4 (10)7 (19)
Nausea5 (11)7 (16)2 (5)3 (8)
Vomiting0 (0)2 (4)0 (0)1 (3)
Headache10 (22)15 (33)7 (17)7 (19)
Malaise6 (13)12 (27)4 (10)4 (11)
Loss of appetite5 (11)10 (22)3 (7)2 (5)