Table 1.

Isolations of C. trachomatis MoPn from control and anti-TNF-α-antibody-treated mice

Mouse groupaIFU (log10[mean ± SD]) on day of infectionb
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C57 control6.2 ± 0.65.5 ± 0.3
C57 + TNF-α antibody6.4 ± 0.45.9 ± 0.5
C57 IFN-γ−/− control6.4 ± 0.35.6 ± 0.6
C57 IFN-γ−/− + TNF-α antibody6.3 ± 0.55.6 ± 0.5
  • a Six female mice per group were infected with 107 IFU of murine MoPn, and isolations were performed from vaginal swabs as described in Materials and Methods.

  • b Means from vaginal swabs of six mice. Results are representative of two separate experiments.