Table 2.

Effect of the vvpE mutation on the lethality of V. vulnificus to normal mice

StrainaIntraperitoneal LD50 (CFU)
Wild typevvpEmutantb
ATCC 29307 (n = 8)1.8 × 107 5.8 × 107
MO6-24/O (n = 10)2.8 × 106 3.8 × 106
  • a Parental V. vulnificusstrain background. n, number of mice for each inoculation group, ranging from 104 to 109 CFU in 10-fold increments.

  • b The vvpE mutants of ATCC 29307 and MO6-24/O are KC64 and CMM111, respectively (see Table 1).