TABLE 1.

Protection after challenge with wild-type S. flexneri 2a 2457T

Immunizing strainNo. of eyes inoculatedNo. of eyes with the indicated ratinga% Protectionb
0123FPC
Normal saline80116000
SC608(p3098)16952056.331.287.5
SC608(pCFAI)161330081.318.7100
SC608(pCFAI/LTB)161222075.012.587.5
  • a 0, no inflammation or mild disease; 1, mild keratoconjunctivitis; 2, keratoconjunctivitis without purulence; 3, severe keratoconjunctivitis with purulence.

  • b F, full; P, partial; and C, combined.