Table 1.

Parasitological data obtained from wild-type and IL-9-expressing transgenic mice with acute or chronic S. mansoni infectionsa

Infection and groupInfectivity (no. of worm pairs)Fecundity (103 eggs per worm pair)No. of eggs in tissue (103/g)No. of eggs excreted into feces
LiverIntestine
Acute
 Wild-type11.3 ± 5.12.4 ± 0.99.6 ± 3.514.7 ± 6.4530 ± 280
 Transgenic10.5 ± 2.82.3 ± 0.69.1 ± 3.314.3 ± 4.7625 ± 377
Chronic
 Wild-type2.3 ± 1.35.3 ± 2.74.8 ± 1.77.4 ± 2.3143 ± 157
 Transgenic2.1 ± 1.46.1 ± 3.14.7 ± 1.58.1 ± 4.0185 ± 140
  • a Parasitological data were obtained from wild-type mice and transgenic mice that constitutively expressed IL-9. Both sets of mice were exposed to acute (150-cercaria) or chronic (25-cercaria) S. mansoni infections. Data are from eight acutely and five chronically infected mice that were killed on days 56 and 72 after infection, respectively. Data are presented as means ± standard deviations and are representative of two separate experiments.