TABLE 3.

Coinfections of mice with nonchemotactic and wild-type H. pyloria

Exp (n)StrainInoculum dose (input) (CFU)Avg CFU/g of stomach (output)Input ratioCompetitive index (output ratio/input ratio)
1 (4) cheW 2.76 × 1064.82 × 1051.130.9
cheA 2.43 × 1064.80 × 105
2 (5) cheW 2.5 × 1071.8 × 1051.390.3
cheY 1.8 × 1074.26 × 105
3 (5)Wild type1.8 × 1073.6 × 1060.3<0.001
cheW 5.3 × 106<100
4 (6)Wild type1.32 × 1074.07 × 1062.260.009
cheW 2.98 × 1078.1 × 104
5A (5)Wild type2.53 × 1072.42 × 1062.39<0.001
cheW 6.05 × 107616
5B (5)Wild type2.53 × 1072.86 × 1060.8<0.001
cheW 2.02 × 107188
5C (5)Wild type2.53 × 1072.16 × 1060.27<0.001
cheW 6.7 × 1061500
6 (4)Wild type8.6 × 1075.74 × 10610.008
cheY 8.6 × 1074.59 × 104
7 (4)Wild type8.6 × 1071.49 × 1061.281.03
cheY/complement1.1 × 1081.96 × 106
  • a Each strain listed under Strain was mixed and coinoculated into mice for 2-week infections. Competitive index is the output ratio (mutant/wild type) divided by the input ratio (mutant/wild type).