TABLE 2.

Granuloma and bacterium counts in lungs of BALB/c and SCID mice infected with 108 Nine Mile strain organisms

Mouse group (inoculum) and day postinfectionMean no./mm2 ± SDa
GranulomasBacteria
BALB/c mice infected with Nine Mile (108 organisms)
    70.84 ± 0.053.15 ± 1.11
    140.12 ± 0.020.24 ± 0.12
SCID mice infected with Nine Mile (108 organisms)
    70.86 ± 0.266.84 ± 2.39
    140.43 ± 0.182.21 ± 0.89
  • a Inflammatory granuloma were numbered after histologic examination with HES staining. Bacteria were numbered by immunohistochemical analysis. Results are expressed as the numbers of granulomas and bacteria of tissue specimens, respectively, as described in Materials and Methods.