TABLE 2.

P. gingivalis genes induced during contact with HEp-2 epithelial cells

ORFGeneProtein or functionRoleFold expression of adherent bacteria/bacteria incubated alone at the following h:
0.7536
PG0045htpGHeat shock protein 90Protein folding and stabilization7.67.767.17
PG0520groELaHeat shock protein 605.1510.083.86
PG0593htrAHeat-induced serine protease2.373.653.23
PG0708FKBPb-type peptidylprolyl isomerase; immunoreactive 30-kDa antigen
PG1208dnaKHeat shock protein 706.673.685.66
PG1315slyDFKBP-type peptidylprolyl isomerase2.514.462.2
PG1775grpEHeat shock protein2.113.721.3
PG1776dnaJHeat shock protein 402.333.723.6
PG0618ahpCAlkyl hydroperoxidase reductase C subunitDetoxification2.63NDcND
PG0619ahpFAlkyl hydroperoxidase reductase F subunit2.22.711.2
PG1134trxBThioredoxin reductase1.133.74.22
PG1545sodBFe-Mn superoxide dismutase2.464.679.3
PG1729tpxThiol peroxidase1.14.173.52
PG1239fabGAcyl carrier proteinFatty acid biosynthesis1.354.651.2
PG1764fabF3-Oxoacyl synthase1.38.763.42
PG1765acpPAcyl carrier protein2.179.684.07
PG1286ftnFerritinTransport and binding proteins4.325.13.24
PG1089rprYTranscriptional regulatorDNA interactions1.23.612.31
PG1240tetRTranscriptional regulator2.676.753.2
PG0192ompH1Cationic outer membrane proteinCell envelope2.813.532.67
PG0193ompH2Cationic outer membrane protein2.884.412.37
PG0435Capsule biosynthesisND1.212.39
PG2167Immunoreactive 53-kDa antigenND6.63.6
PG0506rgpBArg-gingipain BPathogenesisND4.376.54
PG0419Conserved hypotheticalUnknown4.42.912.62
PG0686Conserved hypothetical3.8614.4319.1
PG0434HypotheticalUnknown2.25.712.76
PG0654Hypothetical3.84.473.47
PG1316Hypothetical4.52.12.65
PG1317Hypothetical5.51.12.64
PG1635Hypothetical5.542.02.29
  • a Poor raw images of hybridized groES amplicons resulted in low signal ratios.

  • b FKBP, FK-binding protein.

  • c ND, not detected.