Penetration of 35S-TSST-1 across intact porcine vaginal mucosa in the presence of TSS S. aureus

TreatmentNo. of tissue samples testedTotal toxin penetrating through tissuea (ng)aMaximum flux (ng/cm2/min)a, b
    Live cells9200 ± 182.68 ± 0.40
    Killed cells9115 ± 201.66 ± 0.41
Untreated controls736 ± 7.80.44 ± 0.01
  • a Values are means ± standard error.

  • b Maximum flux was defined as the greatest amount of radiolabeled TSST-1 penetrating across the entire porcine vaginal mucosa per square centimeter of tissue per minute.