TABLE 2.

Chemokines produced by HVECs in response to TSST-1 and other superantigens and inhibition by dodecapeptide

Protein tested (100 μg/ml)Amt of chemokine produced (pg/ml)a
MIP-3αIL-8
None9.0 ± 1.516 ± 1.8
Ovalbumin12 ± 1.836 ± 1.5
TSST-1320 ± 4500 ± 33
SEB470 ± 7620 ± 7
SPEA396 ± 8470 ± 10
Dodecapeptide only9 ± 115 ± 1
TSST-1 only250 ± 7550 ± 8
TSST-1 + dodecapeptideb37 ± 240 ± 3
  • a Values are means ± standard error.

  • b Dodecapeptide concentration was 1,000 μg/ml.