TABLE 2.

Kinetics of NMFTA1 growth and dissemination to reticuloendothelial organsa

Day after infectionLog10F. tularensis cells/organ (CFU)c
LungSpleenLiver
02.30 ± 0.10<2.30b<2.30
14.98 ± 0.04<2.30<2.30
26.52 ± 0.053.40 ± 0.183.57 ± 0.15
37.47 ± 0.126.18 ± 0.566.33 ± 0.44
48.53 ± 0.109.08 ± 0.257.66 ± 0.17
  • a BALB/c mice were inoculated i.n. with approximately 200 CFU of NMFTA1. Three mice were killed on the day of infection (day 0) and four mice were killed every day thereafter to determine the bacterial burdens in the indicated organs.

  • b The limit of detection was 200 CFU.

  • c Data are means ± standard deviations.