TABLE 4.

Intranasal LVS vaccination protected mice against s.c. NMFTA1 challengea

Vaccination statusChallenge dose (CFU)Survival (no. of survivors/no. tested)
None2 × 1020/9
None2 × 1030/4
LVS2 × 1028/9
LVS2 × 1037/9
  • a BALB/c mice were vaccinated i.n. with 200 CFU of LVS and 3 weeks later were challenged s.c. with 2 × 102 or 2 × 103 CFU of NMFTA1. The results show survival ratios on day 30 postchallenge, and all deaths occurred 5 to 6 days after challenge.