TABLE 2.

Immune response analysis of human sera to recombinant TprI antigens

Source of seraaFull-length TprI no. positive/total (%)TprI amino terminus no. positive/total (%)TprI central region no. positive/total (%)TprI carboxyl terminus no. positive/total (%)
Primary syphilis (n = 49)47/49 (96)47/49 (96)0/49 (0)8/49 (16.3)
Secondary syphilis (n = 40)40/40 (100)40/40 (100)0/40 (0)11/40 (27.5)
Late syphilis (n = 57)57/57 (100)57/57 (100)0/57 (0)5/57 (8.7)
Tertiary syphilis (n = 2)2/2 (100)2/2 (100)0/2 (0)2/2 (100)
Unknown stage (n = 2)2/2 (100)2/2 (100)0/2 (0)2/2 (100)
Total (n = 150)148/150 (98.6)148/150 (98.6)0/150 (0)28/150 (18.6)
Blood donors (n = 50)0/50 (0)
  • a The clinical and laboratory guidelines proposed by Norris and Larsen (19) were used to establish the stage of the disease.