TABLE 2.

Systemic and intestinal pathology at 5 days in WT and SPI2 mutant in serovar Typhimurium-infected mice

Pathological changeStrainaP value (t test)
ΔSPI2WT
Cecal wt0.42 ± 0.120.22 ± 0.040.0036
Submucosal edema (% wall thickness)16 ± 448 ± 90.0013
Mucosa (μm)151 ± 18271 ± 290.0010
Spleen wt0.12 ± 0.030.18 ± 0.020.0086
  • a Values shown represent means ± standard deviation for each group.