adhesion
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsComparison of Pathogenicity of Invasive and Carried Meningococcal Isolates of ST-4821 Complex in ChinaSerotype 4821 (ST-4821) clonal complex (cc4821) Neisseria meningitidis strains are divided into two groups (groups I and II) according to the core genome-based phylogenetic analysis. Group I contains the greater number of invasive disease isolates. However, the differences in pathogenicity between the two groups are unclear.
Molecular PathogenesisStreptococcus oralis subsp. dentisani Produces Monolateral Serine-Rich Repeat Protein Fibrils, One of Which Contributes to Saliva Binding via Sialic AcidOur studies reveal that the oral colonizer and cause of infective endocarditis Streptococcus oralis subsp. dentisani displays a striking monolateral distribution of surface fibrils. Furthermore, our data suggest that these fibrils impact the structure of adherent bacterial chains.
Bacterial InfectionsRole of Sialic Acid in Brachyspira hyodysenteriae Adhesion to Pig Colonic MucinsInfection with Brachyspira hyodysenteriae results in mucoid hemorrhagic diarrhea. This pathogen is associated with the colonic mucus layer, mainly composed of mucins.
Molecular PathogenesisThe Edwardsiella piscicida Type III Effector EseJ Suppresses Expression of Type 1 Fimbriae, Leading to Decreased Bacterial Adherence to Host CellsThe type III secretion system (T3SS) of Edwardsiella piscicida plays a crucial role in its pathogenesis. Our previous study indicated that the T3SS effector protein EseJ inhibits the bacterium’s adhesion to epithelioma papillosum cyprini (EPC) cells, while the mechanism of the inhibition remains elusive.
- Fungal and Parasitic Infections | SpotlightRole of the Inducible Adhesin CpAls7 in Binding of Candida parapsilosis to the Extracellular Matrix under Fluid Shear
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsYersinia pestis YopK Inhibits Bacterial Adhesion to Host Cells by Binding to the Extracellular Matrix Adaptor Protein Matrilin-2