antibiotics
MinireviewOuter Membrane Lipid Secretion and the Innate Immune Response to Gram-Negative BacteriaThe outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The asymmetric character and unique biochemistry of LPS molecules contribute to the OM’s ability to function as a molecular permeability barrier that protects the bacterium against hazards in the environment. Assembly and regulation of the OM have been extensively...
Bacterial InfectionsRole of Pseudomonas aeruginosa Glutathione Biosynthesis in Lung and Soft Tissue InfectionThe opportunistic pathogen Pseudomonas aeruginosa is a leading cause of morbidity and mortality worldwide. To survive in both the environment and the host, P. aeruginosa must cope with redox stress. In P. aeruginosa, a primary...
Host-Associated Microbial Communities | SpotlightAntibiotic-Induced Shifts in Fecal Microbiota Density and Composition during Hematopoietic Stem Cell TransplantationDramatic microbiota changes and loss of commensal anaerobic bacteria are associated with adverse outcomes in hematopoietic cell transplantation (HCT) recipients. In this study, we demonstrate these dynamic changes at high resolution through daily stool sampling and assess the impact of individual antibiotics on those changes.
- Host Response and InflammationLactobacillus rhamnosus L34 Attenuates Gut Translocation-Induced Bacterial Sepsis in Murine Models of Leaky Gut
- Host Response and InflammationWhy Antibiotic Treatment Is Not Enough for Sepsis Resolution: an Evaluation in an Experimental Animal Model