apoptosis
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsApoptosis Functions in Defense against Infection of Mammalian Cells with Environmental ChlamydiaeApoptotic cell death can be an efficient defense reaction of mammalian cells infected with obligate intracellular pathogens; the host cell dies and the pathogen cannot replicate. While this is well established for viruses, there is little experimental support for such a concept in bacterial infections. All Chlamydiales are obligate intracellular bacteria, and different species infect vastly different hosts....
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsStenotrophomonas maltophilia Encodes a VirB/VirD4 Type IV Secretion System That Modulates Apoptosis in Human Cells and Promotes Competition against Heterologous Bacteria, Including Pseudomonas aeruginosaStenotrophomonas maltophilia is an emerging opportunistic and nosocomial pathogen. S. maltophilia is also a risk factor for lung exacerbations in cystic fibrosis patients. S. maltophilia attaches to various mammalian cells, and we...
Host Response and InflammationDietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell DeathNeutrophils are the most abundant circulating leukocytes in humans and are essential for the defense against invading pathogens. Like many other cells of an organism, neutrophils can be highly influenced by the diet. We have previously described that mice fed a high-fat diet rich in polyunsaturated fatty acids (HFD-P) present a higher frequency of neutrophils in bone marrow than mice fed a high-fat diet rich in saturated fatty acids (...
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsMethamphetamine Impairs IgG1-Mediated Phagocytosis and Killing of Cryptococcus neoformans by J774.16 Macrophage- and NR-9640 Microglia-Like CellsThe prevalence of methamphetamine (METH) use is estimated at ∼35 million people worldwide, with over 10 million users in the United States. Chronic METH abuse and dependence predispose the users to participate in risky behaviors that may result in the acquisition of HIV and AIDS-related infections.
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsCoxiella burnetii Inhibits Neutrophil Apoptosis by Exploiting Survival Pathways and Antiapoptotic Protein Mcl-1
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsCell Cycle Arrest and Apoptosis Induced by Porphyromonas gingivalis Require Jun N-Terminal Protein Kinase- and p53-Mediated p38 Activation in Human Trophoblasts
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsDiaphorina citri Nymphs Are Resistant to Morphological Changes Induced by “Candidatus Liberibacter asiaticus” in Midgut Epithelial Cells
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsChlamydia trachomatis Cellular Exit Alters Interactions with Host Dendritic Cells
- Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | SpotlightDistinct Roles of the Antiapoptotic Effectors NleB and NleF from Enteropathogenic Escherichia coli
- Microbial Immunity and VaccinesListeria monocytogenes-Induced Cell Death Inhibits the Generation of Cell-Mediated Immunity