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Infection and Immunity
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Aspergillus fumigatus

  • Differential Interactions of Serum and Bronchoalveolar Lavage Fluid Complement Proteins with Conidia of Airborne Fungal Pathogen <span class="named-content genus-species" id="named-content-1">Aspergillus fumigatus</span>
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Differential Interactions of Serum and Bronchoalveolar Lavage Fluid Complement Proteins with Conidia of Airborne Fungal Pathogen Aspergillus fumigatus

    Even though both cellular and humoral immunities contribute to host defense, the role played by humoral immunity against the airborne opportunistic fungal pathogen Aspergillus fumigatus has been underexplored. In this study, we aimed at deciphering the role of the complement system, the major humoral immune component, against...

    Sarah Sze Wah Wong, Irene Daniel, Jean-Pierre Gangneux, Jeya Maheshwari Jayapal, Hélène Guegan, Sarah Dellière, Prajna Lalitha, Rajashri Shende, Taruna Madan, Jagadeesh Bayry, J. Iñaki Guijarro, Dharmalingam Kuppamuthu, Vishukumar Aimanianda
  • <span class="named-content genus-species" id="named-content-1">Aspergillus fumigatus</span> Cell Wall Promotes Apical Airway Epithelial Recruitment of Human Neutrophils
    Host Response and Inflammation
    Aspergillus fumigatus Cell Wall Promotes Apical Airway Epithelial Recruitment of Human Neutrophils

    Aspergillus fumigatus is a ubiquitous fungal pathogen capable of causing multiple pulmonary diseases, including invasive aspergillosis, chronic necrotizing aspergillosis, fungal colonization, and allergic bronchopulmonary aspergillosis. Intact mucociliary barrier function and early airway neutrophil responses are critical for clearing fungal conidia from the host...

    Michael B. Feldman, Richard A. Dutko, Michael A. Wood, Rebecca A. Ward, Hui Min Leung, Ryan F. Snow, Denis J. De La Flor, Lael M. Yonker, Jennifer L. Reedy, Guillermo J. Tearney, Hongmei Mou, Bryan P. Hurley, Jatin M. Vyas
  • Fungal and Parasitic Infections | Spotlight
    The Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus
    Gerard Sheehan, Gudmundur Bergsson, Noel G. McElvaney, Emer P. Reeves, Kevin Kavanagh
  • Host Response and Inflammation
    Acidic Mammalian Chitinase Negatively Affects Immune Responses during Acute and Chronic Aspergillus fumigatus Exposure
    Jaleesa M. Garth, Joseph J. Mackel, Kristen M. Reeder, Jonathan P. Blackburn, Chad W. Dunaway, Zhihong Yu, Sadis Matalon, Lori Fitz, Chad Steele
  • Free
    Host Response and Inflammation | Spotlight
    Interleukin 1α Is Critical for Resistance against Highly Virulent Aspergillus fumigatus Isolates
    Alayna K. Caffrey-Carr, Caitlin H. Kowalski, Sarah R. Beattie, Nathan A. Blaseg, Chanell R. Upshaw, Arsa Thammahong, Hannah E. Lust, Yi-Wei Tang, Tobias M. Hohl, Robert A. Cramer, Joshua J. Obar
  • Fungal and Parasitic Infections | Spotlight
    Secreted Aspergillus fumigatus Protease Alp1 Degrades Human Complement Proteins C3, C4, and C5
    Judith Behnsen, Franziska Lessing, Susann Schindler, Dirk Wartenberg, Ilse D. Jacobsen, Marcel Thoen, Peter F. Zipfel, Axel A. Brakhage
  • Fungal and Parasitic Infections
    Embryonated Eggs as an Alternative Infection Model To Investigate Aspergillus fumigatus Virulence
    Ilse D. Jacobsen, Katharina Große, Silvia Slesiona, Bernhard Hube, Angela Berndt, Matthias Brock
  • Fungal and Parasitic Infections | Spotlight
    Role of Trehalose Biosynthesis in Aspergillus fumigatus Development, Stress Response, and Virulence
    Nadia Al-Bader, Ghyslaine Vanier, Hong Liu, Fabrice N. Gravelat, Mirjam Urb, Christopher M.-Q. Hoareau, Paolo Campoli, Joseé Chabot, Scott G. Filler, Donald C. Sheppard
  • Fungal and Parasitic Infections
    Activation of Platelets by Aspergillus fumigatus and Potential Role of Platelets in the Immunopathogenesis of Aspergillosis
    Ernst Kristian Rødland, Thor Ueland, Turid M. Pedersen, Bente Halvorsen, Fredrik Műller, Pål Aukrust, Stig S. Frøland
  • Fungal and Parasitic Infections
    Aspergillus fumigatus LaeA-Mediated Phagocytosis Is Associated with a Decreased Hydrophobin Layer
    Taylor R. T. Dagenais, Steve S. Giles, Vishukumar Aimanianda, Jean-Paul Latgé, Christina M. Hull, Nancy P. Keller

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