bacterial persistence

  • Open Access
    Increased Mortality in Mice following Immunoprophylaxis Therapy with High Dosage of Nicotinamide in <em>Burkholderia</em> Persistent Infections
    Bacterial Infections
    Increased Mortality in Mice following Immunoprophylaxis Therapy with High Dosage of Nicotinamide in Burkholderia Persistent Infections

    Bacterial persistence, known as noninherited antibacterial resistance, is a factor contributing to the establishment of long-lasting chronic bacterial infections. In this study, we examined the ability of nicotinamide (NA) to potentiate the activity of different classes of antibiotics against Burkholderia thailandensis persister cells.

    Sofiya N. Micheva-Viteva, Brittany N. Ross, Jun Gao, Samantha Adikari, Pengfei Zhang, Judith R. Mourant, Terry H. Wu, James H. Werner, Alfredo G. Torres, Elizabeth Hong-Geller
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