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Infection and Immunity
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BCG vaccine

  • Open Access
    Curcumin Nanoparticles Enhance <span class="named-content genus-species" id="named-content-1">Mycobacterium bovis</span> BCG Vaccine Efficacy by Modulating Host Immune Responses
    Microbial Immunity and Vaccines
    Curcumin Nanoparticles Enhance Mycobacterium bovis BCG Vaccine Efficacy by Modulating Host Immune Responses

    Tuberculosis (TB) is one of the deadliest diseases, causing ∼2 million deaths annually worldwide. Mycobacterium bovis bacillus Calmette-Guérin (BCG), the only TB vaccine in common use, is effective against disseminated and meningeal TB in young children but is not effective against adult pulmonary TB.

    Shaheer Ahmad, Debapriya Bhattacharya, Santosh Kar, Anand Ranganathan, Luc Van Kaer, Gobardhan Das
  • Microbial Immunity and Vaccines
    Surface Expression of MPT64 as a Fusion with the PE Domain of PE_PGRS33 Enhances Mycobacterium bovis BCG Protective Activity against Mycobacterium tuberculosis in Mice
    Michela Sali, Gabriele Di Sante, Alessandro Cascioferro, Antonella Zumbo, Chiara Nicolò, Valentina Donà, Stefano Rocca, Annabella Procoli, Matteo Morandi, Francesco Ria, Giorgio Palù, Giovanni Fadda, Riccardo Manganelli, Giovanni Delogu
  • Host Response and Inflammation
    Mycobacterium bovis BCG-Specific Th17 Cells Confer Partial Protection against Mycobacterium tuberculosis Infection in the Absence of Gamma Interferon
    Teresa M. Wozniak, Bernadette M. Saunders, Anthony A. Ryan, Warwick J. Britton
  • Host Response and Inflammation
    Kinetics of the Immune Response Profile in Guinea Pigs after Vaccination with Mycobacterium bovis BCG and Infection with Mycobacterium tuberculosis
    Ajay Grover, Jennifer Taylor, JoLynn Troudt, Andrew Keyser, Kimberly Arnett, Linda Izzo, Drew Rholl, Angelo Izzo
  • Molecular Genomics
    A Comprehensive Survey of Single Nucleotide Polymorphisms (SNPs) across Mycobacterium bovis Strains and M. bovis BCG Vaccine Strains Refines the Genealogy and Defines a Minimal Set of SNPs That Separate Virulent M. bovis Strains and M. bovis BCG Strains
    M. Carmen Garcia Pelayo, Swapna Uplekar, Andrew Keniry, Pablo Mendoza Lopez, Thierry Garnier, Javier Nunez Garcia, Laura Boschiroli, Xiangmei Zhou, Julian Parkhill, Noel Smith, R. Glyn Hewinson, Stewart T. Cole, Stephen V. Gordon
  • Microbial Immunity and Vaccines
    Immunogenicity and Protective Efficacy of Prime-Boost Regimens with Recombinant ΔureC hly+Mycobacterium bovis BCG and Modified Vaccinia Virus Ankara Expressing M. tuberculosis Antigen 85A against Murine Tuberculosis
    Elma Z. Tchilian, Christiane Desel, Emily K. Forbes, Silke Bandermann, Clare R. Sander, Adrian V. S. Hill, Helen McShane, Stefan H. E. Kaufmann
  • Microbial Immunity and Vaccines
    A Replication-Limited Recombinant Mycobacterium bovis BCG Vaccine against Tuberculosis Designed for Human Immunodeficiency Virus-Positive Persons Is Safer and More Efficacious than BCG
    Michael V. Tullius, Günter Harth, Saša Masleša-Galić, Barbara J. Dillon, Marcus A. Horwitz
  • Microbial Immunity and Vaccines
    Mycobacterium bovis BCG Immunization Induces Protective Immunity against Nine Different Mycobacterium tuberculosis Strains in Mice
    Bo Young Jeon, Steven C. Derrick, JaeHyun Lim, Kristopher Kolibab, Veerabadran Dheenadhayalan, Amy Li Yang, Barry Kreiswirth, Sheldon L. Morris
  • Microbial Immunity and Vaccines
    Oral Vaccination of Guinea Pigs with a Mycobacterium bovis Bacillus Calmette-Guérin Vaccine in a Lipid Matrix Protects against Aerosol Infection with Virulent M. bovis
    Simon Clark, Martin L. Cross, Allan Nadian, Julia Vipond, Pinar Court, Ann Williams, R. Glyn Hewinson, Frank E. Aldwell, Mark A. Chambers
  • Microbial Immunity and Vaccines
    Mycobacterium bovis BCG Vaccine Strains Lack narK2 and narX Induction and Exhibit Altered Phenotypes during Dormancy
    Ryan W. Honaker, Amanda Stewart, Stephanie Schittone, Angelo Izzo, Michèl R. Klein, Martin I. Voskuil

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