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bile

  • The Great ESKAPE: Exploring the Crossroads of Bile and Antibiotic Resistance in Bacterial Pathogens
    Minireview | Spotlight
    The Great ESKAPE: Exploring the Crossroads of Bile and Antibiotic Resistance in Bacterial Pathogens

    Throughout the course of infection, many pathogens encounter bactericidal conditions that threaten the viability of the bacteria and impede the establishment of infection. Bile is one of the most innately bactericidal compounds present in humans, functioning to reduce the bacterial burden in the gastrointestinal tract while also aiding in digestion. It is becoming increasingly apparent that pathogens successfully resist the bactericidal...

    Kevin S. Gipson, Kourtney P. Nickerson, Eliana Drenkard, Alejandro Llanos-Chea, Snaha Krishna Dogiparthi, Bernard B. Lanter, Rhianna M. Hibbler, Lael M. Yonker, Bryan P. Hurley, Christina S. Faherty
  • The Autotransporter IcsA Promotes <span class="named-content genus-species" id="named-content-1">Shigella flexneri</span> Biofilm Formation in the Presence of Bile Salts
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    The Autotransporter IcsA Promotes Shigella flexneri Biofilm Formation in the Presence of Bile Salts

    Shigella flexneri is an intracellular bacterial pathogen that invades epithelial cells in the colonic mucosa, leading to bloody diarrhea. A previous study showed that S. flexneri forms biofilms in the presence of bile salts, through an unknown mechanism.

    Volkan K. Köseoğlu, Chelsea P. Hall, Eric M. Rodríguez-López, Hervé Agaisse
  • Molecular Pathogenesis
    vttRA and vttRB Encode ToxR Family Proteins That Mediate Bile-Induced Expression of Type Three Secretion System Genes in a Non-O1/Non-O139 Vibrio cholerae Strain
    Ashfaqul Alam, Vincent Tam, Elaine Hamilton, Michelle Dziejman
  • Molecular Pathogenesis
    Specific Osmolyte Transporters Mediate Bile Tolerance in Listeria monocytogenes
    Debbie Watson, Roy D. Sleator, Pat G. Casey, Colin Hill, Cormac G. M. Gahan
  • Molecular Pathogenesis
    Identification of a Bile-Induced Exopolysaccharide Required for Salmonella Biofilm Formation on Gallstone Surfaces
    Robert W. Crawford, Deanna L. Gibson, William W. Kay, John S. Gunn
  • Molecular Pathogenesis
    Effect of Fatty Acids and Cholesterol Present in Bile on Expression of Virulence Factors and Motility of Vibrio cholerae
    Arpita Chatterjee, Pradeep K. Dutta, Rukhsana Chowdhury
  • Molecular Pathogenesis
    Role of the Histone-Like Nucleoid Structuring Protein in Colonization, Motility, and Bile-Dependent Repression of Virulence Gene Expression in Vibrio cholerae
    Amalendu Ghosh, Kalidas Paul, Rukhsana Chowdhury
  • Molecular Pathogenesis
    Contribution of Three Bile-Associated Loci, bsh, pva, and btlB, to Gastrointestinal Persistence and Bile Tolerance of Listeria monocytogenes
    Máire Begley, Roy D. Sleator, Cormac G. M. Gahan, Colin Hill
  • Molecular Pathogenesis
    Critical Role of Multidrug Efflux Pump CmeABC in Bile Resistance and In Vivo Colonization of Campylobacter jejuni
    Jun Lin, Orhan Sahin, Linda Overbye Michel, Qijing Zhang
  • Molecular Pathogenesis
    Vibrio cholerae OmpU and OmpT Porins Are Differentially Affected by Bile
    Jamie A. Wibbenmeyer, Daniele Provenzano, Candice F. Landry, Karl E. Klose, Anne H. Delcour

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