bile
- Minireview | SpotlightThe Great ESKAPE: Exploring the Crossroads of Bile and Antibiotic Resistance in Bacterial Pathogens
Throughout the course of infection, many pathogens encounter bactericidal conditions that threaten the viability of the bacteria and impede the establishment of infection. Bile is one of the most innately bactericidal compounds present in humans, functioning to reduce the bacterial burden in the gastrointestinal tract while also aiding in digestion. It is becoming increasingly apparent that pathogens successfully resist the bactericidal...
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsThe Autotransporter IcsA Promotes Shigella flexneri Biofilm Formation in the Presence of Bile Salts
Shigella flexneri is an intracellular bacterial pathogen that invades epithelial cells in the colonic mucosa, leading to bloody diarrhea. A previous study showed that S. flexneri forms biofilms in the presence of bile salts, through an unknown mechanism.
- Molecular PathogenesisSpecific Osmolyte Transporters Mediate Bile Tolerance in Listeria monocytogenes
- Molecular PathogenesisVibrio cholerae OmpU and OmpT Porins Are Differentially Affected by Bile