biofilms
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsA Nonfimbrial Adhesin of Aggregatibacter actinomycetemcomitans Mediates Biofilm BiogenesisPeriodontitis is an inflammatory disease caused by polymicrobial biofilms. The periodontal pathogen Aggregatibacter actinomycetemcomitans displays two proteinaceous surface structures, the fimbriae and the nonfimbrial extracellular matrix binding protein A (EmaA), as observed by electron microscopy.
Molecular GenomicsGenomic, Phenotypic, and Virulence Analysis of Streptococcus sanguinis Oral and Infective-Endocarditis IsolatesStreptococcus sanguinis, an abundant and benign inhabitant of the oral cavity, is an important etiologic agent of infective endocarditis (IE), particularly in people with predisposing cardiac valvular damage. Although commonly isolated from patients with IE, little is known about the factors that make any particular...
- Microbial Immunity and Vaccines | SpotlightStandardization of Pneumococcal Biofilm Release to PncO Expression, a Predictive Measurement of Virulence
A critical component in clinical trials for vaccines against pneumococcal disease is the establishment of robust preclinical models and clinical correlates of protection, which, in the case of the causative bacterial agent Streptococcus pneumoniae, include standard sepsis/pneumonia mouse models and opsonophagocytic activity (OPA), respectively. Despite broad usage,...
- Bacterial InfectionsModel of Chronic Equine Endometritis Involving a Pseudomonas aeruginosa Biofilm
- Letter to the EditorReply to Brennan, “Biofilms and Mycobacterium tuberculosis”
- Letter to the EditorBiofilms and Mycobacterium tuberculosis