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Infection and Immunity
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caspases

  • <span class="named-content genus-species" id="named-content-1">Salmonella enterica</span> Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes
    Host Response and Inflammation
    Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes

    Recent studies have determined that inflammasome signaling plays an important role in driving intestinal epithelial cell (IEC) responses to bacterial infections, such as Salmonella enterica serovar Typhimurium. There are two primary inflammasome pathways, canonical (involving caspase-1) and noncanonical (involving caspase-4 and -5 in humans and caspase-11 in mice)....

    Mayumi K. Holly, Xiao Han, Edward J. Zhao, Shauna M. Crowley, Joannie M. Allaire, Leigh A. Knodler, Bruce A. Vallance, Jason G. Smith
  • Host Response and Inflammation
    Caspase-11 Plays a Protective Role in Pulmonary Acinetobacter baumannii Infection
    Wei Wang, Yue Shao, Shengjun Li, Na Xin, Tingxian Ma, Chenghai Zhao, Min Song
  • Open Access
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    SipA Activation of Caspase-3 Is a Decisive Mediator of Host Cell Survival at Early Stages of Salmonella enterica Serovar Typhimurium Infection
    Anne McIntosh, Lynsey M. Meikle, Michael J. Ormsby, Beth A. McCormick, John M. Christie, James M. Brewer, Mark Roberts, Daniel M. Wall
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Cytolethal Distending Toxin Induces Caspase-Dependent and -Independent Cell Death in MOLT-4 Cells
    Masaru Ohara, Tomonori Hayashi, Yoichiro Kusunoki, Kei Nakachi, Tamaki Fujiwara, Hitoshi Komatsuzawa, Motoyuki Sugai
  • Host Response and Inflammation
    Host-Dependent Trigger of Caspases and Apoptosis by Legionella pneumophila
    Marina Santic, Rexford Asare, Miljenko Doric, Yousef Abu Kwaik
  • Molecular Pathogenesis
    Genetic Susceptibility and Caspase Activation in Mouse and Human Macrophages Are Distinct for Legionella longbeachae and L. pneumophila
    Rexford Asare, Marina Santic, Ivana Gobin, Miljenko Doric, Jill Suttles, James E. Graham, Christopher D. Price, Yousef Abu Kwaik
  • Molecular Pathogenesis
    Mannheimia haemolytica Leukotoxin Induces Apoptosis of Bovine Lymphoblastoid Cells (BL-3) via a Caspase-9-Dependent Mitochondrial Pathway
    Dhammika N. Atapattu, Charles J. Czuprynski
  • Molecular Pathogenesis
    Shiga Toxin 1 Induces Apoptosis in the Human Myelogenous Leukemia Cell Line THP-1 by a Caspase-8-Dependent, Tumor Necrosis Factor Receptor-Independent Mechanism
    Sang-Yun Lee, Rama P. Cherla, Isa Caliskan, Vernon L. Tesh
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Chlamydia pneumoniae Augments the Oxidized Low-Density Lipoprotein-Induced Death of Mouse Macrophages by a Caspase-Independent Pathway
    Kambiz Yaraei, Lee Ann Campbell, Xiaodong Zhu, W. Conrad Liles, Cho-chou Kuo, Michael E. Rosenfeld
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    The B Subunit of Escherichia coli Heat-Labile Enterotoxin Induces Both Caspase-Dependent and -Independent Cell Death Pathways in CD8+ T Cells
    Robert J. Salmond, Rachel Williams, Timothy R. Hirst, Neil A. Williams

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