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chemotaxis

  • Morphological and Motility Features of the Stable Bleb-Driven Monopodial Form of <em>Entamoeba</em> and Its Importance in Encystation
    Fungal and Parasitic Infections
    Morphological and Motility Features of the Stable Bleb-Driven Monopodial Form of Entamoeba and Its Importance in Encystation

    Entamoeba histolytica and its reptilian counterpart and encystation model Entamoeba invadens formed a polarized monopodial morphology when treated with pentoxifylline. This morphology was propelled by retrograde flow of the cell surface resulting from a cyclic sol-gel conversion of cytoplasm and a...

    Deepak Krishnan, Sudip Kumar Ghosh
  • The Msp Protein of <span class="named-content genus-species" id="named-content-1">Treponema denticola</span> Interrupts Activity of Phosphoinositide Processing in Neutrophils
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    The Msp Protein of Treponema denticola Interrupts Activity of Phosphoinositide Processing in Neutrophils

    Periodontal disease is a significant health burden, causing tooth loss and poor oral and overall systemic health. Dysbiosis of the oral biofilm and a dysfunctional immune response drive chronic inflammation, causing destruction of soft tissue and alveolar bone supporting the teeth. Treponema denticola, a spirochete abundant in the plaque biofilm of patients with...

    Megan M. Jones, Stephen T. Vanyo, Michelle B. Visser
  • <span class="named-content genus-species" id="named-content-1">Helicobacter pylori</span> Uses the TlpB Receptor To Sense Sites of Gastric Injury
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Helicobacter pylori Uses the TlpB Receptor To Sense Sites of Gastric Injury

    Helicobacter pylori is a pathogen that chronically colonizes the stomachs of approximately half of the world’s population and contributes to the development of gastric inflammation. We demonstrated previously in vivo that H. pylori uses motility to preferentially colonize injury sites in...

    Hikaru Hanyu, Kristen A. Engevik, Andrea L. Matthis, Karen M. Ottemann, Marshall H. Montrose, Eitaro Aihara
  • Dietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell Death
    Host Response and Inflammation
    Dietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell Death

    Neutrophils are the most abundant circulating leukocytes in humans and are essential for the defense against invading pathogens. Like many other cells of an organism, neutrophils can be highly influenced by the diet. We have previously described that mice fed a high-fat diet rich in polyunsaturated fatty acids (HFD-P) present a higher frequency of neutrophils in bone marrow than mice fed a high-fat diet rich in saturated fatty acids (...

    Sara L. Svahn, Saray Gutiérrez, Marcus A. Ulleryd, Intawat Nookaew, Veronica Osla, Fredrik Beckman, Staffan Nilsson, Anna Karlsson, John-Olov Jansson, Maria E. Johansson
  • Molecular Pathogenesis
    The Norepinephrine Metabolite 3,4-Dihydroxymandelic Acid Is Produced by the Commensal Microbiota and Promotes Chemotaxis and Virulence Gene Expression in Enterohemorrhagic Escherichia coli
    Nitesh Sule, Sasi Pasupuleti, Nandita Kohli, Rani Menon, Lawrence J. Dangott, Michael D. Manson, Arul Jayaraman
  • Molecular Pathogenesis
    Borrelia burgdorferi CheY2 Is Dispensable for Chemotaxis or Motility but Crucial for the Infectious Life Cycle of the Spirochete
    Hui Xu, Syed Sultan, Aaron Yerke, Ki Hwan Moon, R. Mark Wooten, M. A. Motaleb
  • Host Response and Inflammation | Spotlight
    Anthrax Edema Toxin Induces Maturation of Dendritic Cells and Enhances Chemotaxis towards Macrophage Inflammatory Protein 3β
    Francisco J. Maldonado-Arocho, Kenneth A. Bradley
  • Host Response and Inflammation
    Gingipains from Porphyromonas gingivalis Increase the Chemotactic and Respiratory Burst-Priming Properties of the 77-Amino-Acid Interleukin-8 Variant
    Irundika H. K. Dias, Lindsay Marshall, Peter A. Lambert, Iain L. C. Chapple, John B. Matthews, Helen R. Griffiths
  • Bacterial Infections
    Differential Effects of Epinephrine, Norepinephrine, and Indole on Escherichia coli O157:H7 Chemotaxis, Colonization, and Gene Expression
    Tarun Bansal, Derek Englert, Jintae Lee, Manjunath Hegde, Thomas K. Wood, Arul Jayaraman
  • Host Response and Inflammation
    Helicobacter pylori Chemotaxis Modulates Inflammation and Bacterium-Gastric Epithelium Interactions in Infected Mice
    Susan M. Williams, Yu-Ting Chen, Tessa M. Andermann, J. Elliot Carter, David J. McGee, Karen M. Ottemann

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