chemotaxis
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsHelicobacter pylori Uses the TlpB Receptor To Sense Sites of Gastric InjuryHelicobacter pylori is a pathogen that chronically colonizes the stomachs of approximately half of the world’s population and contributes to the development of gastric inflammation. We demonstrated previously in vivo that H. pylori uses motility to preferentially colonize injury sites in...
Host Response and InflammationDietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell DeathNeutrophils are the most abundant circulating leukocytes in humans and are essential for the defense against invading pathogens. Like many other cells of an organism, neutrophils can be highly influenced by the diet. We have previously described that mice fed a high-fat diet rich in polyunsaturated fatty acids (HFD-P) present a higher frequency of neutrophils in bone marrow than mice fed a high-fat diet rich in saturated fatty acids (...