Coccidioides
Microbial Immunity and Vaccines | SpotlightGlucan-Chitin Particles Enhance Th17 Response and Improve Protective Efficacy of a Multivalent Antigen (rCpa1) against Pulmonary Coccidioides posadasii InfectionDeveloping an effective and safe recombinant vaccine requires microbe-specific antigens combined with an adjuvant/delivery system to strengthen protective immunity. In this study, we designed and expressed a multivalent recombinant Coccidioides polypeptide antigen (rCpa1) that consists of three previously identified antigens (i.e., Ag2/Pra, Cs-Ag, and Pmp1) and five...
- Fungal and Parasitic Infections | SpotlightMyeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis
- Fungal and Parasitic InfectionsA Genetically Engineered Live Attenuated Vaccine of Coccidioides posadasii Protects BALB/c Mice against Coccidioidomycosis
- Fungal and Parasitic Infections | SpotlightEvaluation of Two Homologous Proline-Rich Proteins of Coccidioides posadasii as Candidate Vaccines against Coccidioidomycosis
- Fungal and Parasitic InfectionsMultivalent Recombinant Protein Vaccine against Coccidioidomycosis
- Fungal and Parasitic InfectionsSpherules Derived from Coccidioides posadasii Promote Human Dendritic Cell Maturation and Activation
- Fungal and Parasitic InfectionsUrease Produced by Coccidioides posadasii Contributes to the Virulence of This Respiratory Pathogen
- Fungal and Parasitic InfectionsA Recombinant Aspartyl Protease of Coccidioides posadasii Induces Protection against Pulmonary Coccidioidomycosis in Mice
- Fungal and Parasitic InfectionsA Metalloproteinase of Coccidioides posadasii Contributes to Evasion of Host Detection