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Infection and Immunity
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colon

  • Adoptive Transfer of Group 3-Like Innate Lymphoid Cells Restores Mouse Colon Resistance to Colonization of a Gamma Interferon-Susceptible <span class="named-content genus-species" id="named-content-1">Chlamydia muridarum</span> Mutant
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Adoptive Transfer of Group 3-Like Innate Lymphoid Cells Restores Mouse Colon Resistance to Colonization of a Gamma Interferon-Susceptible Chlamydia muridarum Mutant

    The obligate intracellular bacterium Chlamydia muridarum can colonize the mouse colon for a long period, but a gamma interferon (IFN-γ)-susceptible mutant clone fails to do so. Nevertheless, the mutant’s colonization is rescued in mice deficient in interleukin-7 receptor (IL-7R) (lacking both lymphocytes and innate lymphoid cells [ILCs]) or IFN-γ but not in mice...

    Ying He, Hong Xu, Chenchen Song, John J. Koprivsek, Bernard Arulanandam, Huixiang Yang, Lijian Tao, Guangming Zhong
  • Role of Sialic Acid in <span class="named-content genus-species" id="named-content-1">Brachyspira hyodysenteriae</span> Adhesion to Pig Colonic Mucins
    Bacterial Infections
    Role of Sialic Acid in Brachyspira hyodysenteriae Adhesion to Pig Colonic Mucins

    Infection with Brachyspira hyodysenteriae results in mucoid hemorrhagic diarrhea. This pathogen is associated with the colonic mucus layer, mainly composed of mucins.

    Macarena P. Quintana-Hayashi, Vignesh Venkatakrishnan, Freddy Haesebrouck, Sara Lindén
  • Molecular Pathogenesis | Spotlight
    Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide
    Steven D. Zumbrun, Leanne Hanson, James F. Sinclair, James Freedy, Angela R. Melton-Celsa, Jaime Rodriguez-Canales, Jeffrey C. Hanson, Alison D. O'Brien
  • Bacterial Infections
    Community-Wide Response of the Gut Microbiota to Enteropathogenic Citrobacter rodentium Infection Revealed by Deep Sequencing
    Christian Hoffmann, David A. Hill, Nana Minkah, Thomas Kirn, Amy Troy, David Artis, Frederic Bushman
  • Bacterial Infections
    Decreased Expression of Colonic Slc26a3 and Carbonic Anhydrase IV as a Cause of Fatal Infectious Diarrhea in Mice
    Diana Borenshtein, Katherine A. Schlieper, Barry H. Rickman, Jeannie M. Chapman, Clifford W. Schweinfest, James G. Fox, David B. Schauer
  • Molecular Pathogenesis
    Effects of Clostridium perfringens Beta-Toxin on the Rabbit Small Intestine and Colon
    Jorge E. Vidal, Bruce A. McClane, Juliann Saputo, Jaquelyn Parker, Francisco A. Uzal
  • Molecular Pathogenesis
    gp96 Is a Human Colonocyte Plasma Membrane Binding Protein for Clostridium difficile Toxin A
    Xi Na, Ho Kim, Mary P. Moyer, Charalabos Pothoulakis, J. Thomas LaMont
  • Host Response and Inflammation | Spotlight
    Surface Expression of Toll-Like Receptor 9 Is Upregulated on Intestinal Epithelial Cells in Response to Pathogenic Bacterial DNA
    Julia B. Ewaschuk, Jody L. Backer, Thomas A. Churchill, Florian Obermeier, Denis O. Krause, Karen L. Madsen
  • Fungal and Parasitic Infections
    Induction of Monocyte Chemotactic Protein 1 in Colonic Epithelial Cells by Entamoeba histolytica Is Mediated via the Phosphatidylinositol 3-Kinase/p65 Pathway
    Srinivas J. Kammanadiminti, Indranil Dey, Kris Chadee
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Disruption of Tight Junctions and Induction of Proinflammatory Cytokine Responses in Colonic Epithelial Cells by Campylobacter jejuni
    Ming L. Chen, Zhongming Ge, James G. Fox, David B. Schauer

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