cytokines
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsInteraction of Gardnerella vaginalis and Vaginolysin with the Apical versus Basolateral Face of a Three-Dimensional Model of Vaginal EpitheliumStudies have implicated Gardnerella vaginalis as an important etiological agent in bacterial vaginosis (BV). It produces a cholesterol-dependent cytolysin, vaginolysin (VLY).
Host Response and InflammationImmunologic Pathways in Protective versus Maladaptive Host Responses to Attenuated and Pathogenic Strains of Mycoplasma gallisepticumMycoplasmas are small bacterial commensals or pathogens that commonly colonize host mucosal tissues and avoid rapid clearance, in part by stimulating inflammatory, immunopathogenic responses. We previously characterized a wide array of transcriptomic perturbations in avian host tracheal mucosae infected with virulent, immunopathologic Mycoplasma gallisepticum; however...
Bacterial InfectionsViable Coxiella burnetii Induces Differential Cytokine Responses in Chronic Q Fever Patients Compared to Heat-Killed Coxiella burnetiiCytokine responses of chronic Q fever patients to the intracellular bacterium Coxiella burnetii have mostly been studied using ex vivo stimulation of immune cells with heat-killed C. burnetii due to the extensive measures needed to work with viable biosafety level 3 agents. Whether research...
- Host Response and InflammationInterleukin-17A Exacerbates Disease Severity in BALB/c Mice Susceptible to Lung Infection with Mycoplasma pulmonis
Mycoplasmas are atypical bacteria that disrupt the immune response to promote respiratory tract infections and secondary complications. However, not every immunologic response that protects or damages the host during mycoplasma infection is known.
- Host Response and InflammationHuman Interleukin-32γ Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice
- Fungal and Parasitic InfectionsGenetic Polymorphisms in Cytokine Genes in Colombian Patients with Ocular Toxoplasmosis
- Fungal and Parasitic InfectionsDifferential In Vitro Cytokine Induction by the Species of Cryptococcus gattii Complex