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Infection and Immunity
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enterotoxins

  • <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span> Isolated from Skin from Atopic-Dermatitis Patients Produces Staphylococcal Enterotoxin Y, Which Predominantly Induces T-Cell Receptor Vα-Specific Expansion of T Cells
    Molecular Pathogenesis
    Staphylococcus aureus Isolated from Skin from Atopic-Dermatitis Patients Produces Staphylococcal Enterotoxin Y, Which Predominantly Induces T-Cell Receptor Vα-Specific Expansion of T Cells

    While investigating the virulence traits of Staphylococcus aureus adhering to the skin of atopic-dermatitis (AD) patients, we identified a novel open reading frame (ORF) with structural similarity to a superantigen from genome sequence data of an isolate from AD skin. Concurrently, the same ORF was identified in a bovine isolate of...

    Fatkhanuddin Aziz, Junzo Hisatsune, Liansheng Yu, Junko Kajimura, Yusuke Sato’o, Hisaya K. Ono, Kanako Masuda, Mika Yamaoka, Siti Isrina Oktavia Salasia, Akio Nakane, Hiroki Ohge, Yoichiro Kusunoki, Motoyuki Sugai
  • Porcine Gastric Mucin Triggers Toxin Production of Enteropathogenic <em>Bacillus cereus</em>
    Bacterial Infections
    Porcine Gastric Mucin Triggers Toxin Production of Enteropathogenic Bacillus cereus

    Enteropathogenic Bacillus cereus causes foodborne infections due to the production of pore-forming enterotoxins in the intestine. Before that, spores have to be ingested, survive the stomach passage, and germinate.

    Nadja Jessberger, Richard Dietrich, Ann-Katrin Mohr, Claudia Da Riol, Erwin Märtlbauer
  • Bacterial Infections
    Transforming Growth Factor β1/SMAD Signaling Pathway Activation Protects the Intestinal Epithelium from Clostridium difficile Toxin A-Induced Damage
    Christianne Maria Tinoco-Veras, Ana Angélica Q. A. Santos, Joice Stipursky, Marcelo Meloni, Ana Paula Bérgamo Araujo, Danielle Abreu Foschetti, Diana López-Ureña, Carlos Quesada-Gómez, Renata F. C. Leitão, Flávia Carvalho Alcantara Gomes, Gerly Anne de Castro Brito
  • Molecular Pathogenesis
    The Agr-Like Quorum Sensing System Is Required for Pathogenesis of Necrotic Enteritis Caused by Clostridium perfringens in Poultry
    Qiang Yu, Dion Lepp, Iman Mehdizadeh Gohari, Tao Wu, Hongzhuan Zhou, Xianhua Yin, Hai Yu, John F. Prescott, Shao-Ping Nie, Ming-Yong Xie, Joshua Gong
  • Microbial Immunity and Vaccines
    Mucosal Antibodies to the C Terminus of Toxin A Prevent Colonization of Clostridium difficile
    Huynh A. Hong, Krisztina Hitri, Siamand Hosseini, Natalia Kotowicz, Donna Bryan, Fatme Mawas, Anthony J. Wilkinson, Annie van Broekhoven, Jonathan Kearsey, Simon M. Cutting
  • Molecular Pathogenesis
    CodY Promotes Sporulation and Enterotoxin Production by Clostridium perfringens Type A Strain SM101
    Jihong Li, John C. Freedman, Daniel R. Evans, Bruce A. McClane
  • Bacterial Infections
    LT-IIc, a New Member of the Type II Heat-Labile Enterotoxin Family Encoded by an Escherichia coli Strain Obtained from a Nonmammalian Host
    Hesham F. Nawar, Natalie D. King-Lyons, John C. Hu, Raymond C. Pasek, Terry D. Connell
  • Molecular Pathogenesis
    Evaluating the Involvement of Alternative Sigma Factors SigF and SigG in Clostridium perfringens Sporulation and Enterotoxin Synthesis
    Jihong Li, Bruce A. McClane
  • Molecular Pathogenesis
    Cytotoxicity of the Bacillus cereus Nhe Enterotoxin Requires Specific Binding Order of Its Three Exoprotein Components
    Toril Lindbäck, Simon P. Hardy, Richard Dietrich, Marianne Sødring, Andrea Didier, Maximilian Moravek, Annette Fagerlund, Stefanie Bock, Carina Nielsen, Maximilian Casteel, Per Einar Granum, Erwin Märtlbauer
  • Molecular Pathogenesis
    The VirSR Two-Component Signal Transduction System Regulates NetB Toxin Production in Clostridium perfringens
    Jackie K. Cheung, Anthony L. Keyburn, Glen P. Carter, Anouk L. Lanckriet, Filip Van Immerseel, Robert J. Moore, Julian I. Rood

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