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Infection and Immunity
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Francisella tularensis

  • Molecular Pathogenesis
    Francisella tularensis ΔpyrF Mutants Show that Replication in Nonmacrophages Is Sufficient for Pathogenesis In Vivo
    Joseph Horzempa, Dawn M. O'Dee, Robert M. Q. Shanks, Gerard J. Nau
  • Host Response and Inflammation | Spotlight
    Indoleamine 2,3-Dioxygenase 1 Is a Lung-Specific Innate Immune Defense Mechanism That Inhibits Growth of Francisella tularensis Tryptophan Auxotrophs
    Kaitian Peng, Denise M. Monack
  • Host Response and Inflammation
    GroEL and Lipopolysaccharide from Francisella tularensis Live Vaccine Strain Synergistically Activate Human Macrophages
    Courtney E. Noah, Meenakshi Malik, DeAnna C. Bublitz, Devin Camenares, Timothy J. Sellati, Jorge L. Benach, Martha B. Furie
  • Host Response and Inflammation
    Toll-Like Receptor 3 Agonist Protection against Experimental Francisella tularensis Respiratory Tract Infection
    Richard B. Pyles, G. Eric Jezek, Tonyia D. Eaves-Pyles
  • Host Response and Inflammation
    A tolC Mutant of Francisella tularensis Is Hypercytotoxic Compared to the Wild Type and Elicits Increased Proinflammatory Responses from Host Cells
    Gabrielle J. Platz, DeAnna C. Bublitz, Patricio Mena, Jorge L. Benach, Martha B. Furie, David G. Thanassi
  • Microbial Immunity and Vaccines | Spotlight
    The Presence of CD14 Overcomes Evasion of Innate Immune Responses by Virulent Francisella tularensis in Human Dendritic Cells In Vitro and Pulmonary Cells In Vivo
    Jennifer C. Chase, Catharine M. Bosio
  • Molecular Pathogenesis | Spotlight
    Acid Phosphatases Do Not Contribute to the Pathogenesis of Type A Francisella tularensis
    Robert Child, Tara D. Wehrly, Dedeke Rockx-Brouwer, David W. Dorward, Jean Celli
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Francisella tularensis Induces Ubiquitin-Dependent Major Histocompatibility Complex Class II Degradation in Activated Macrophages
    Justin E. Wilson, Bhuvana Katkere, James R. Drake
  • Host Response and Inflammation
    Francisella tularensis Induces Extensive Caspase-3 Activation and Apoptotic Cell Death in the Tissues of Infected Mice
    Jason R. Wickstrum, Sirosh M. Bokhari, Jeffrey L. Fischer, David M. Pinson, Hung-Wen Yeh, Rebecca T. Horvat, Michael J. Parmely
  • Microbial Immunity and Vaccines
    Vaccination with an Attenuated Strain of Francisella novicida Prevents T-Cell Depletion and Protects Mice Infected with the Wild-Type Strain from Severe Sepsis
    Jyotika Sharma, Qun Li, Bibhuti B. Mishra, Michelle J. Georges, Judy M. Teale

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