gene expression
Molecular PathogenesisDiffusible Signal Factors Act through AraC-Type Transcriptional Regulators as Chemical Cues To Repress Virulence of Enteric PathogensSuccessful colonization by enteric pathogens is contingent upon effective interactions with the host and the resident microbiota. These pathogens thus respond to and integrate myriad signals to control virulence. Long-chain fatty acids repress the virulence of the important enteric pathogens Salmonella enterica and...
Molecular PathogenesisThe Lon-1 Protease Is Required by Borrelia burgdorferi To Infect the Mammalian HostBorrelia burgdorferi encodes a functional homolog of canonical Lon protease termed Lon-2. In addition, B. burgdorferi encodes a second Lon homolog called Lon-1. Recent studies suggest that Lon-1 may function differently from the prototypical Lon protease. However, the function of Lon-1 in...
- Host Response and InflammationPerforin Expression by CD8 T Cells Is Sufficient To Cause Fatal Brain Edema during Experimental Cerebral Malaria
- Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | SpotlightThe Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1
- Fungal and Parasitic Infections | SpotlightImpairment of Host Defense against Disseminated Candidiasis in Mice Overexpressing GATA-3