innate immunity
Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsCoxiella burnetii Blocks Intracellular Interleukin-17 Signaling in MacrophagesCoxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole membrane into the host cytoplasm, where they...
Host Response and InflammationDepletion of Complement Enhances the Clearance of Brucella abortus in MiceBrucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement.
- Fungal and Parasitic Infections | SpotlightThe Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus
- Fungal and Parasitic Infections | SpotlightMyeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis
- Host Response and InflammationThioester-Containing Proteins 2 and 4 Affect the Metabolic Activity and Inflammation Response in Drosophila
- Bacterial InfectionsA Natural Mouse Model for Neisseria Colonization
- Host Response and InflammationNeutrophils from Both Susceptible and Resistant Mice Efficiently Kill Opsonized Listeria monocytogenes