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Infection and Immunity
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Leishmania mexicana

  • Differential Regulation of <span class="sc">l</span>-Arginine Metabolism through Arginase 1 during Infection with <span class="named-content genus-species" id="named-content-1">Leishmania mexicana</span> Isolates Obtained from Patients with Localized and Diffuse Cutaneous Leishmaniasis
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Differential Regulation of l-Arginine Metabolism through Arginase 1 during Infection with Leishmania mexicana Isolates Obtained from Patients with Localized and Diffuse Cutaneous Leishmaniasis

    l-Arginine metabolism through arginase 1 (Arg-1) and inducible nitric oxide synthase (NOS2) constitutes a fundamental axis for the resolution or progression of leishmaniasis. Infection with Leishmania mexicana can cause two distinct clinical manifestations: localized cutaneous leishmaniasis (LCL) and diffuse cutaneous leishmaniasis (DCL). In...

    Arturo A. Wilkins-Rodríguez, Armando Pérez-Torres, Alma R. Escalona-Montaño, Laila Gutiérrez-Kobeh
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Comparative Study of the Ability of Leishmania mexicana Promastigotes and Amastigotes To Alter Macrophage Signaling and Functions
    Issa Abu-Dayyeh, Kasra Hassani, Edze R. Westra, Jeremy C. Mottram, Martin Olivier
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Overexpression of the Natural Inhibitor of Cysteine Peptidases in Leishmania mexicana Leads to Reduced Virulence and a Th1 Response
    Karen Bryson, Sébastien Besteiro, H. Adrienne McGachy, Graham H. Coombs, Jeremy C. Mottram, James Alexander
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    FcγRIII Mediates Immunoglobulin G-Induced Interleukin-10 and Is Required for Chronic Leishmania mexicana Lesions
    Bolaji N. Thomas, Laurence U. Buxbaum
  • Fungal and Parasitic Infections
    l-Arginine and Cationic Amino Acid Transporter 2B Regulate Growth and Survival of Leishmania amazonensis Amastigotes in Macrophages
    Nanchaya Wanasen, Carol L. MacLeod, Lesley G. Ellies, Lynn Soong
  • Fungal and Parasitic Infections
    Leishmania pifanoi Amastigotes Avoid Macrophage Production of Superoxide by Inducing Heme Degradation
    Nam-Kha Pham, Jennifer Mouriz, Peter E. Kima
  • Fungal and Parasitic Infections
    CD4+ T Cells Play a Dominant Role in Protection against New World Leishmaniasis Induced by Vaccination with the P-4 Amastigote Antigen
    Sujata Kar, Christine Metz, Diane McMahon-Pratt
  • Fungal and Parasitic Infections
    Interleukin 10- and Fcγ Receptor-Deficient Mice Resolve Leishmania mexicana Lesions
    Laurence U. Buxbaum, Phillip Scott
  • Fungal and Parasitic Infections
    Sand Fly Saliva Enhances Leishmania amazonensis Infection by Modulating Interleukin-10 Production
    Nilufer B. Norsworthy, Jiaren Sun, Dia Elnaiem, Gregory Lanzaro, Lynn Soong
  • Fungal and Parasitic Infections
    Enhanced Replication of Leishmania amazonensis Amastigotes in Gamma Interferon-Stimulated Murine Macrophages: Implications for the Pathogenesis of Cutaneous Leishmaniasis
    Hai Qi, Jiaxiang Ji, Nanchaya Wanasen, Lynn Soong

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