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liver injury

  • STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway
    Fungal and Parasitic Infections
    STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway

    Schistosomiasis is a parasitic helminth disease that can cause organ lesions leading to health damage. During a schistosome infection, schistosome eggs can flow into the liver along the portal vein.

    Jie Zhao, Xin Liu, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Deng-Ren Ji, Shi-Meng Liu, Mo-Zhi Jia, Yong-Hong Zhu, Yong-Fen Qi, Feng-Min Lu, Yan-Rong Yu
  • Taurine Alleviates Schistosoma-Induced Liver Injury by Inhibiting the TXNIP/NLRP3 Inflammasome Signal Pathway and Pyroptosis
    Fungal and Parasitic Infections
    Taurine Alleviates Schistosoma-Induced Liver Injury by Inhibiting the TXNIP/NLRP3 Inflammasome Signal Pathway and Pyroptosis

    Schistosomiasis is a parasitic helminth disease that can cause severe inflammatory pathology, leading to organ damage, in humans. During a schistosomal infection, the eggs are trapped in the host liver, and products derived from eggs induce a polarized Th2 cell response, resulting in granuloma formation and eventually fibrosis.

    Xin Liu, Ya-Rong Zhang, Chen Cai, Xian-Qiang Ni, Qing Zhu, Jin-Ling Ren, Yao Chen, Lin-Shuang Zhang, Chang-Ding Xue, Jie Zhao, Yong-Fen Qi, Yan-Rong Yu
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