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Infection and Immunity
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liver stage

  • Open Access
    Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span> LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria
    Microbial Immunity and Vaccines
    Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria

    Despite promising progress in malaria vaccine development in recent years, an efficacious subunit vaccine against Plasmodium falciparum remains to be licensed and deployed. Cell-mediated protection from liver-stage malaria relies on a sufficient number of antigen-specific T cells reaching the liver during the time that parasites are present. A single vaccine...

    Benedict R. Halbroth, Sarah Sebastian, Ahmed M. Salman, Marta Ulaszewska, Anita Gola, Rhea J. Longley, Chris J. Janse, Shahid M. Khan, Adrian V. S. Hill, Alexandra J. Spencer
  • Open Access
    Microbial Immunity and Vaccines | Spotlight
    The Complement System Contributes to Functional Antibody-Mediated Responses Induced by Immunization with Plasmodium falciparum Malaria Sporozoites
    Marije C. Behet, Liriye Kurtovic, Geert-Jan van Gemert, Celine M. Haukes, Rianne Siebelink-Stoter, Wouter Graumans, Marga G. van de Vegte-Bolmer, Anja Scholzen, Jeroen D. Langereis, Dimitri A. Diavatopoulos, James G. Beeson, Robert W. Sauerwein
  • Microbial Immunity and Vaccines
    A Plasmodium Parasite with Complete Late Liver Stage Arrest Protects against Preerythrocytic and Erythrocytic Stage Infection in Mice
    Ashley M. Vaughan, Brandon K. Sack, Dorender Dankwa, Nana Minkah, Thao Nguyen, Hayley Cardamone, Stefan H. I. Kappe
  • Open Access
    Microbial Immunity and Vaccines
    Assessment of the Plasmodium falciparum Preerythrocytic Antigen UIS3 as a Potential Candidate for a Malaria Vaccine
    Rhea J. Longley, Benedict R. Halbroth, Ahmed M. Salman, Katie J. Ewer, Susanne H. Hodgson, Chris J. Janse, Shahid M. Khan, Adrian V. S. Hill, Alexandra J. Spencer
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