lung
Host Response and Inflammation | SpotlightDifferential Induction of Type I and III Interferons by Staphylococcus aureusStaphylococcus aureus is a leading cause of bacterial pneumonia, and we have shown previously that type I interferon (IFN) contributes to the pathogenesis of this disease. In this study, we screened 75 S. aureus strains for their ability to induce type I and III IFN. Both cytokine pathways were...
Host Response and InflammationTransbronchial Invasion and Proliferation of Leptospira interrogans in Lung without Inflammatory Cell Infiltration in a Hamster ModelLeptospirosis caused by pathogenic Leptospira is one of the most common zoonoses in the world. It is believed that humans become infected with it mainly through their skin and mucous membranes by contact with water or soil that is contaminated with urine excreted from infected animals. Recently, outbreaks have frequently occurred in the tropics, especially after flooding, but how leptospires cause mass infection remains poorly...
Host Response and Inflammation | SpotlightRole of Common γ-Chain Cytokines in Lung Interleukin-22 Regulation after Acute Exposure to Aspergillus fumigatusHumans are constantly exposed to the opportunistic mold Aspergillus fumigatus, and disease caused by this pathogen is often determined by the magnitude of local and systemic immune responses. We have previously shown a protective role for interleukin-22 (IL-22) after acute A. fumigatus exposure....
- Fungal and Parasitic InfectionsTumor Necrosis Factor Alpha Antagonism Reveals a Gut/Lung Axis That Amplifies Regulatory T Cells in a Pulmonary Fungal Infection
- Host Response and Inflammation | SpotlightInterleukin 1α Is Critical for Resistance against Highly Virulent Aspergillus fumigatus Isolates
- Host Response and Inflammation | SpotlightKilling of Pseudomonas aeruginosa by Chicken Cathelicidin-2 Is Immunogenically Silent, Preventing Lung Inflammation In Vivo
- Host Response and InflammationCytosolic Phospholipase A2α Promotes Pulmonary Inflammation and Systemic Disease during Streptococcus pneumoniae Infection
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsImmune Recognition of the Epidemic Cystic Fibrosis Pathogen Burkholderia dolosa
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsStaphylococcus aureus Survives in Cystic Fibrosis Macrophages, Forming a Reservoir for Chronic Pneumonia