microbiota
Microbial Immunity and VaccinesCommensal Microbes Affect Host Humoral Immunity to Bordetella pertussis InfectionAs important players in the host defense system, commensal microbes and the microbiota influence multiple aspects of host physiology. Bordetella pertussis infection is highly contagious among humans. However, the roles of the microbiota in B. pertussis pathogenesis are poorly understood. Here, we...
MinireviewTaming the Beast: Interplay between Gut Small Molecules and Enteric PathogensThe overuse of antibiotics has led to the evolution of drug-resistant bacteria that are becoming increasingly dangerous to human health. According to the Centers for Disease Control and Prevention, antibiotic-resistant bacteria cause at least 2 million illnesses and 23,000 deaths in the United States annually. Traditionally, antibiotics are bactericidal or bacteriostatic agents that place selective pressure on bacteria, leading to the...
Host Response and InflammationSuppression of Obesity by an Intestinal Helminth through Interactions with Intestinal MicrobiotaObesity is increasingly causing lifestyle diseases in developed countries where helminthic infections are rarely seen. Here, we investigated whether an intestinal nematode, Heligmosomoides polygyrus, has a suppressive role in diet-induced obesity in mice.
- Host-Associated Microbial CommunitiesGut Microbiome Analysis Identifies Potential Etiological Factors in Acute Gastroenteritis