Mycobacterium marinum
Molecular PathogenesisConserved ESX-1 Substrates EspE and EspF Are Virulence Factors That Regulate Gene ExpressionMycobacterium tuberculosis, the cause of human tuberculosis, and Mycobacterium marinum, a nontubercular pathogen with a broad host range, require the ESX-1 secretion system for virulence. The ESX-1 system secretes proteins which cause phagosomal lysis within the macrophage via an unknown mechanism....
Molecular PathogenesisThe ESX-1 Virulence Factors Downregulate miR-147-3p in Mycobacterium marinum-Infected MacrophagesAs important virulence factors of Mycobacterium tuberculosis, EsxA and EsxB not only play a role in phagosome rupture and M. tuberculosis cytosolic translocation but also function as modulators of host immune responses by modulating numerous microRNAs (miRNAs). Recently, we have found that...
- Molecular PathogenesisA Nonsense Mutation in Mycobacterium marinum That Is Suppressible by a Novel Mechanism
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsEvidence for Pore Formation in Host Cell Membranes by ESX-1-Secreted ESAT-6 and Its Role in Mycobacterium marinum Escape from the Vacuole
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsUse of Gene Dosage Effects for a Whole-Genome Screen To Identify Mycobacterium marinum Macrophage Infection Loci
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsA Mycobacterial Gene Involved in Synthesis of an Outer Cell Envelope Lipid Is a Key Factor in Prevention of Phagosome Maturation
- Host Response and Inflammation | SpotlightMycobacterium marinum Infection of Adult Zebrafish Causes Caseating Granulomatous Tuberculosis and Is Moderated by Adaptive Immunity
- Cellular Microbiology: Pathogen-Host Cell Molecular InteractionsMycobacterium marinum Erp Is a Virulence Determinant Required for Cell Wall Integrity and Intracellular Survival