MyD88
Molecular PathogenesisImmediate Interferon Gamma Induction Determines Murine Host Compatibility Differences between Toxoplasma gondii and Neospora caninumRodents are critical for the transmission of Toxoplasma gondii to the definitive feline host via predation, and this relationship has been extensively studied as a model for immune responses to parasites. Neospora caninum is a closely related coccidian parasite of ruminants and canines but is not...
Host Response and InflammationYersinia pestis Exploits Early Activation of MyD88 for Growth in the Lungs during Pneumonic PlagueYersinia pestis causes bubonic, pneumonic, and septicemic plague. Although no longer responsible for pandemic outbreaks, pneumonic plague continues to be a challenge for medical treatment and has been classified as a reemerging disease in some parts of the world.
- Fungal and Parasitic Infections | SpotlightMyeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis
- Host Response and InflammationInduction of Type I Interferon through a Noncanonical Toll-Like Receptor 7 Pathway during Yersinia pestis Infection
- Host Response and InflammationTemporal Role for MyD88 in a Model of Brucella-Induced Arthritis and Musculoskeletal Inflammation