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nitric oxide synthase

  • Toll-Like Receptor 2-Tpl2-Dependent ERK Signaling Drives Inverse Interleukin 12 Regulation in Dendritic Cells and Macrophages
    Host Response and Inflammation
    Toll-Like Receptor 2-Tpl2-Dependent ERK Signaling Drives Inverse Interleukin 12 Regulation in Dendritic Cells and Macrophages

    This study investigated responses to Toll-like receptor 2 (TLR2)-driven extracellular signal-related kinase (ERK) signaling in dendritic cells (DCs) versus macrophages. TLR2 signaling was induced with Pam3Cys-Ser-Lys4, and the role of ERK signaling was interrogated pharmacologically with MEK1/2 inhibitor U0126 or genetically with bone marrow-derived macrophages or DCs from Tpl2−/− mice. We...

    Sarah G. Groft, Nancy Nagy, W. Henry Boom, Clifford V. Harding
  • Open Access
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | Spotlight
    Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling
    Aimin Wu, Piotr Tymoszuk, David Haschka, Simon Heeke, Stefanie Dichtl, Verena Petzer, Markus Seifert, Richard Hilbe, Sieghart Sopper, Heribert Talasz, Dirk Bumann, Cornelia Lass-Flörl, Igor Theurl, Keying Zhang, Guenter Weiss
  • Fungal and Parasitic Infections
    Induction of Nitric Oxide Synthase and Activation of Signaling Proteins in Anopheles Mosquitoes by the Malaria Pigment, Hemozoin
    Leyla Akman-Anderson, Martin Olivier, Shirley Luckhart
  • Fungal and Parasitic Infections
    Induction of Nitric Oxide Synthase in Anopheles stephensi by Plasmodium falciparum: Mechanism of Signaling and the Role of Parasite Glycosylphosphatidylinositols
    Junghwa Lim, D. Channe Gowda, Gowdahalli Krishnegowda, Shirley Luckhart
  • Bacterial Infections
    Gastric Helicobacter Infection Induces a Th2 Phenotype but Does Not Elevate Serum Cholesterol in Mice Lacking Inducible Nitric Oxide Synthase
    Melanie Ihrig, Mark T. Whary, Charles A. Dangler, James G. Fox
  • Fungal and Parasitic Infections
    Susceptibility of Germfree Phagocyte Oxidase- and Nitric Oxide Synthase 2-Deficient Mice, Defective in the Production of Reactive Metabolites of Both Oxygen and Nitrogen, to Mucosal and Systemic Candidiasis of Endogenous Origin
    Edward Balish, Thomas F. Warner, Peter J. Nicholas, Emily E. Paulling, Caroline Westwater, David A. Schofield
  • Fungal and Parasitic Infections
    Nitric Oxide Production and Nitric Oxide Synthase Activity in Malaria-Exposed Papua New Guinean Children and Adults Show Longitudinal Stability and No Association with Parasitemia
    Craig S. Boutlis, J. Brice Weinberg, Joanne Baker, Moses J. Bockarie, Charles S. Mgone, Qin Cheng, Nicholas M. Anstey
  • Host Response and Inflammation
    Both Inducible Nitric Oxide Synthase and NADPH Oxidase Contribute to the Control of Virulent Phase I Coxiella burnetii Infections
    Robert E. Brennan, Kasi Russell, Guoquan Zhang, James E. Samuel
  • Fungal and Parasitic Infections
    Elevated Nitric Oxide Production in Children with Malarial Anemia: Hemozoin-Induced Nitric Oxide Synthase Type 2 Transcripts and Nitric Oxide in Blood Mononuclear Cells
    Christopher C. Keller, Peter G. Kremsner, James B. Hittner, Mary A. Misukonis, J. Brice Weinberg, Douglas J. Perkins
  • Host Response and Inflammation
    Inhibition of Nitric Oxide Synthase Exacerbates Group B Streptococcus Sepsis and Arthritis in Mice
    Manuela Puliti, Christina von Hunolstein, Francesco Bistoni, Graziella Orefici, Luciana Tissi

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