Skip to main content
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems
  • Log in
  • My alerts
  • My Cart

Main menu

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About IAI
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems

User menu

  • Log in
  • My alerts
  • My Cart

Search

  • Advanced search
Infection and Immunity
publisher-logosite-logo

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About IAI
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions

Plasmodium falciparum

  • Open Access
    Microscopic and Submicroscopic Asymptomatic <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span> Infections in Ghanaian Children and Protection against Febrile Malaria
    Fungal and Parasitic Infections
    Microscopic and Submicroscopic Asymptomatic Plasmodium falciparum Infections in Ghanaian Children and Protection against Febrile Malaria

    Naturally acquired immunity to Plasmodium falciparum malaria is thought to be nonsterile and sustained by persistence of low-level parasitemia. This study assessed the association between baseline microscopic and submicroscopic asymptomatic P. falciparum infections and antimalarial antibody levels...

    Bright Adu, Quratul-ain Issahaque, Tracy Sarkodie-Addo, Selassie Kumordjie, Eric Kyei-Baafour, Caleb K. Sinclear, Sophia Eyia-Ampah, Eunice Owusu-Yeboa, Michael Theisen, Daniel Dodoo
  • <em>In Vivo</em> Imaging of the Buccal Mucosa Shows Loss of the Endothelial Glycocalyx and Perivascular Hemorrhages in Pediatric <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span> Malaria
    Host Response and Inflammation
    In Vivo Imaging of the Buccal Mucosa Shows Loss of the Endothelial Glycocalyx and Perivascular Hemorrhages in Pediatric Plasmodium falciparum Malaria

    Severe malaria is mostly caused by Plasmodium falciparum, resulting in considerable, systemic inflammation and pronounced endothelial activation. The endothelium forms an interface between blood and tissue, and vasculopathy has previously been linked with malaria severity. We studied the extent to which the endothelial glycocalyx that normally maintains endothelial...

    Eric Lyimo, Lars Emil Haslund, Thomas Ramsing, Christian William Wang, Akinwale Michael Efunshile, Alphaxard Manjurano, Victor Makene, John Lusingu, Thor Grundtvig Theander, Jørgen Anders Lindholm Kurtzhals, Rasmus Paulsen, Casper Hempel
  • Antimalarial Activity of Human Group IIA Secreted Phospholipase A<sub>2</sub> in Relation to Enzymatic Hydrolysis of Oxidized Lipoproteins
    Molecular Pathogenesis
    Antimalarial Activity of Human Group IIA Secreted Phospholipase A2 in Relation to Enzymatic Hydrolysis of Oxidized Lipoproteins

    The level of human group IIA secreted phospholipase A2 (hGIIA sPLA2) is increased in the plasma of malaria patients, but its role is unknown. In parasite culture with normal plasma, hGIIA is inactive against Plasmodium falciparum, contrasting with hGIIF, hGV, and hGX sPLA2s, which readily hydrolyze plasma lipoproteins, release...

    Mélanie Dacheux, Véronique Sinou, Christine Payré, Louise Jeammet, Daniel Parzy, Philippe Grellier, Christiane Deregnaucourt, Gérard Lambeau
  • Open Access
    Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span> Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C

    Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important malaria virulence factor. The protein family can be divided into clinically relevant subfamilies. ICAM-1-binding group A PfEMP1 proteins also bind endothelial protein C receptor and have been associated with cerebral malaria in children. IgG to these PfEMP1 proteins is acquired later in life...

    Rebecca W. Olsen, Gertrude Ecklu-Mensah, Anja Bengtsson, Michael F. Ofori, Kwadwo A. Kusi, Kwadwo A. Koram, Lars Hviid, Yvonne Adams, Anja T. R. Jensen
  • Functional Antibodies against Placental Malaria Parasites Are Variant Dependent and Differ by Geographic Region
    Microbial Immunity and Vaccines
    Functional Antibodies against Placental Malaria Parasites Are Variant Dependent and Differ by Geographic Region

    During pregnancy, Plasmodium falciparum-infected erythrocytes (IE) accumulate in the intervillous spaces of the placenta by binding to chondroitin sulfate A (CSA) and elicit inflammatory responses that are associated with poor pregnancy outcomes. Primigravidae lack immunity to IE that sequester in the placenta and thus are susceptible to placental malaria (PM).

    ...
    Justin Doritchamou, Andrew Teo, Robert Morrison, Gunjan Arora, Jennifer Kwan, Javier Manzella-Lapeira, Sarimar Medina-Maldonado, Jean Langhorne, Lars Hviid, David L. Narum, Alassane Dicko, Michal Fried, Patrick E. Duffy
  • Transmission-Blocking Vaccines: Old Friends and New Prospects
    Minireview
    Transmission-Blocking Vaccines: Old Friends and New Prospects

    In the progression of the life cycle of Plasmodium falciparum, a small proportion of asexual parasites differentiate into male or female sexual forms called gametocytes. Just like their asexual counterparts, gametocytes are contained within the infected host’s erythrocytes (RBCs).

    Festus K. Acquah, Joshua Adjah, Kim C. Williamson, Linda E. Amoah
  • Combining Monophosphoryl Lipid A (MPL), CpG Oligodeoxynucleotide (ODN), and QS-21 Adjuvants Induces Strong and Persistent Functional Antibodies and T Cell Responses against Cell-Traversal Protein for Ookinetes and Sporozoites (CelTOS) of <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span> in BALB/c Mice
    Fungal and Parasitic Infections
    Combining Monophosphoryl Lipid A (MPL), CpG Oligodeoxynucleotide (ODN), and QS-21 Adjuvants Induces Strong and Persistent Functional Antibodies and T Cell Responses against Cell-Traversal Protein for Ookinetes and Sporozoites (CelTOS) of Plasmodium falciparum in BALB/c Mice

    Plasmodium falciparum cell-traversal protein for ookinetes and sporozoites (PfCelTOS) is an advanced vaccine candidate that has a crucial role in the traversal of the malaria parasite in both mosquito and mammalian hosts. As recombinant purified proteins are normally poor immunogens, they require to be admixed with an adjuvant(s); therefore, the objective of the...

    Sakineh Pirahmadi, Sedigheh Zakeri, Akram A. Mehrizi, Navid D. Djadid, Abbas-Ali Raz, Jafar J. Sani
  • Moderately Neutralizing Epitopes in Nonfunctional Regions Dominate the Antibody Response to <em>Plasmodium falciparum</em> EBA-140
    Microbial Immunity and Vaccines
    Moderately Neutralizing Epitopes in Nonfunctional Regions Dominate the Antibody Response to Plasmodium falciparum EBA-140

    Plasmodium falciparum erythrocyte-binding antigen 140 (EBA-140) plays a role in tight junction formation during parasite invasion of red blood cells and is a potential vaccine candidate for malaria. Individuals in areas where malaria is endemic possess EBA-140-specific antibodies, and individuals with high antibody titers to this protein have a lower rate of...

    Nichole D. Salinas, May M. Paing, Jagat Adhikari, Michael L. Gross, Niraj Tolia
  • Kinetic and Cross-Sectional Studies on the Genesis of Hypoargininemia in Severe Pediatric <em>Plasmodium falciparum</em> Malaria
    Fungal and Parasitic Infections
    Kinetic and Cross-Sectional Studies on the Genesis of Hypoargininemia in Severe Pediatric Plasmodium falciparum Malaria

    The low bioavailability of nitric oxide (NO) and its precursor, arginine, contributes to the microvascular pathophysiology of severe falciparum malaria. To better characterize the mechanisms underlying hypoargininemia in severe malaria, we measured the plasma concentrations of amino acids involved in de novo arginine synthesis in children with uncomplicated falciparum malaria (UM; n = 61), children with cerebral...

    Matthew P. Rubach, Haoyue Zhang, Salvatore M. Florence, Jackson P. Mukemba, Ayam R. Kalingonji, Nicholas M. Anstey, Tsin W. Yeo, Bert K. Lopansri, J. Will Thompson, Esther D. Mwaikambo, Sarah Young, David S. Millington, J. Brice Weinberg, Donald L. Granger
  • Mosquito Bite-Induced Controlled Human Malaria Infection with <span class="named-content genus-species" id="named-content-1">Plasmodium vivax</span> or <span class="named-content genus-species" id="named-content-2">P. falciparum</span> Generates Immune Responses to Homologous and Heterologous Preerythrocytic and Erythrocytic Antigens
    Fungal and Parasitic Infections
    Mosquito Bite-Induced Controlled Human Malaria Infection with Plasmodium vivax or P. falciparum Generates Immune Responses to Homologous and Heterologous Preerythrocytic and Erythrocytic Antigens

    Seroepidemiological studies on the prevalence of antibodies to malaria antigens are primarily conducted on individuals from regions of endemicity. It is therefore difficult to accurately correlate the antibody responses to the timing and number of prior malaria infections.

    Cysha E. Hall, Lisa M. Hagan, Elke Bergmann-Leitner, Donna M. Tosh, Jason W. Bennett, Jason A. Regules, Ilin Chuang, Evelina Angov, Sheetij Dutta, Debasish Chattopadhyay, Anjali Yadava

Pages

  • Next
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
  • 9
  • …
  • 28
Back to top

About

  • About IAI
  • Editor in Chief
  • Editorial Board
  • Policies
  • For Reviewers
  • For the Media
  • For Librarians
  • For Advertisers
  • Alerts
  • RSS
  • FAQ
  • Permissions
  • Journal Announcements

Authors

  • ASM Author Center
  • Submit a Manuscript
  • Article Types
  • Ethics
  • Contact Us

Follow #IAIjournal

@ASMicrobiology

       

ASM Journals

ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology.

About ASM | Contact Us | Press Room

 

ASM is a member of

Scientific Society Publisher Alliance

 

American Society for Microbiology
1752 N St. NW
Washington, DC 20036
Phone: (202) 737-3600

Copyright © 2021 American Society for Microbiology | Privacy Policy | Website feedback

Print ISSN: 0019-9567; Online ISSN: 1098-5522