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Salmonella typhi

  • Generation and Characterization of Typhoid Toxin-Neutralizing Human Monoclonal Antibodies
    Molecular Pathogenesis
    Generation and Characterization of Typhoid Toxin-Neutralizing Human Monoclonal Antibodies

    Typhoid toxin is a virulence factor of Salmonella enterica serovar Typhi, the causative agent of typhoid fever, and is thought to be responsible for the symptoms of severe disease. This toxin has a unique A2B5 architecture with two active subunits, the ADP ribosyl transferase PltA and the DNase CdtB, linked to a pentameric B subunit, which is alternatively made of...

    Xuyao Jiao, Sarah Smith, Gabrielle Stack, Qi Liang, Allan Bradley, Paul Kellam, Jorge E. Galán
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    New Insights into the Roles of Long Polar Fimbriae and Stg Fimbriae in Salmonella Interactions with Enterocytes and M Cells
    Amanda M. Gonzales, Shyra Wilde, Kenneth L. Roland
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Vacuolation Activity and Intracellular Trafficking of ArtB, the Binding Subunit of an AB5 Toxin Produced by Salmonella enterica Serovar Typhi
    Brock P. Herdman, James C. Paton, Hui Wang, Travis Beddoe, Adrienne W. Paton
  • Open Access
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Salmonella enterica Serovar Typhi Lipopolysaccharide O-Antigen Modification Impact on Serum Resistance and Antibody Recognition
    Erica Kintz, Christian Heiss, Ian Black, Nicholas Donohue, Naj Brown, Mark R. Davies, Parastoo Azadi, Stephen Baker, Paul M. Kaye, Marjan van der Woude
  • Bacterial Infections
    The Salmonella enterica Serotype Typhi Vi Capsular Antigen Is Expressed after the Bacterium Enters the Ileal Mucosa
    Quynh T. Tran, Gabriel Gomez, Sangeeta Khare, Sara D. Lawhon, Manuela Raffatellu, Andreas J. Bäumler, Dharani Ajithdoss, Soma Dhavala, L. Garry Adams
  • Microbial Immunity and Vaccines
    A New Generation of Stable, Nonantibiotic, Low-Copy-Number Plasmids Improves Immune Responses to Foreign Antigens in Salmonella enterica Serovar Typhi Live Vectors
    James E. Galen, Jin Yuan Wang, Magaly Chinchilla, Christopher Vindurampulle, Jeffrey E. Vogel, Haim Levy, William C. Blackwelder, Marcela F. Pasetti, Myron M. Levine
  • Host Response and Inflammation
    The Capsule-Encoding viaB Locus Reduces Intestinal Inflammation by a Salmonella Pathogenicity Island 1-Independent Mechanism
    Takeshi Haneda, Sebastian E. Winter, Brian P. Butler, R. Paul Wilson, Çagla Tükel, Maria G. Winter, Ivan Godinez, Renée M. Tsolis, Andreas J. Bäumler
  • Microbial Immunity and Vaccines
    Anthrax Protective Antigen Delivered by Salmonella enterica Serovar Typhi Ty21a Protects Mice from a Lethal Anthrax Spore Challenge
    Manuel Osorio, Yanping Wu, Sunil Singh, Tod J. Merkel, Siba Bhattacharyya, Milan S. Blake, Dennis J. Kopecko
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Abelson Tyrosine Kinase Facilitates Salmonella enterica Serovar Typhimurium Entry into Epithelial Cells
    Kim Thien Ly, James E. Casanova
  • Molecular Pathogenesis
    Identification of a Bile-Induced Exopolysaccharide Required for Salmonella Biofilm Formation on Gallstone Surfaces
    Robert W. Crawford, Deanna L. Gibson, William W. Kay, John S. Gunn

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