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Infection and Immunity
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Salmonella Typhimurium

  • Clarithromycin Exerts an Antibiofilm Effect against <em>Salmonella enterica</em> Serovar Typhimurium rdar Biofilm Formation and Transforms the Physiology towards an Apparent Oxygen-Depleted Energy and Carbon Metabolism
    Bacterial Infections
    Clarithromycin Exerts an Antibiofilm Effect against Salmonella enterica Serovar Typhimurium rdar Biofilm Formation and Transforms the Physiology towards an Apparent Oxygen-Depleted Energy and Carbon Metabolism

    Upon biofilm formation, production of extracellular matrix components and alteration in physiology and metabolism allows bacteria to build up multicellular communities which can facilitate nutrient acquisition during unfavorable conditions and provide protection toward various forms of environmental stresses to individual cells. Thus, bacterial cells within biofilms become tolerant against antimicrobials and the immune system. In the...

    Munirah Zafar, Humera Jahan, Sulman Shafeeq, Manfred Nimtz, Lothar Jänsch, Ute Römling, M. Iqbal Choudhary
  • Improved Tolerability of a <span class="named-content genus-species" id="named-content-1">Salmonella enterica</span> Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity
    Microbial Immunity and Vaccines
    Improved Tolerability of a Salmonella enterica Serovar Typhimurium Live-Attenuated Vaccine Strain Achieved by Balancing Inflammatory Potential with Immunogenicity

    A notable proportion of Salmonella-associated gastroenteritis in the United States is attributed to Salmonella enterica serovar Typhimurium. We have previously shown that live-attenuated S.

    Ellen E. Higginson, Girish Ramachandran, Aruna Panda, Steven T. Shipley, Edwin H. Kriel, Louis J. DeTolla, Michael Lipsky, Darren J. Perkins, Rosangela Salerno-Goncalves, Marcelo B. Sztein, Marcela F. Pasetti, Myron M. Levine, Sharon M. Tennant
  • Open Access
    Microbial Immunity and Vaccines
    Antigen Localization Influences the Magnitude and Kinetics of Endogenous Adaptive Immune Response to Recombinant Salmonella Vaccines
    Yanina R. Sevastsyanovich, David R. Withers, Claire L. Marriott, Faye C. Morris, Timothy J. Wells, Douglas F. Browning, Irene Beriotto, Ewan Ross, Hossam Omar Ali, Catherine A. Wardius, Adam F. Cunningham, Ian R. Henderson, Amanda E. Rossiter
  • Minireview
    Bacterial Chat: Intestinal Metabolites and Signals in Host-Microbiota-Pathogen Interactions
    Bruna C. Lustri, Vanessa Sperandio, Cristiano G. Moreira
  • Open Access
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | Spotlight
    Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling
    Aimin Wu, Piotr Tymoszuk, David Haschka, Simon Heeke, Stefanie Dichtl, Verena Petzer, Markus Seifert, Richard Hilbe, Sieghart Sopper, Heribert Talasz, Dirk Bumann, Cornelia Lass-Flörl, Igor Theurl, Keying Zhang, Guenter Weiss
  • Microbial Immunity and Vaccines
    Th17-Mediated Cross Protection against Pneumococcal Carriage by Vaccination with a Variable Antigen
    Kirsten Kuipers, Wouter S. P. Jong, Christa E. van der Gaast-de Jongh, Diane Houben, Fred van Opzeeland, Elles Simonetti, Saskia van Selm, Ronald de Groot, Marije I. Koenders, Taj Azarian, Elder Pupo, Peter van der Ley, Jeroen D. Langereis, Aldert Zomer, Joen Luirink, Marien I. de Jonge
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Host and Pathogen Copper-Transporting P-Type ATPases Function Antagonistically during Salmonella Infection
    Erik Ladomersky, Aslam Khan, Vinit Shanbhag, Jennifer S. Cavet, Jefferson Chan, Gary A. Weisman, Michael J. Petris
  • Host Response and Inflammation
    Hepcidin-(In)dependent Mechanisms of Iron Metabolism Regulation during Infection by Listeria and Salmonella
    Ana C. Moreira, João V. Neves, Tânia Silva, Patrícia Oliveira, Maria S. Gomes, Pedro N. Rodrigues
  • Open Access
    Microbial Immunity and Vaccines
    Role of sapA and yfgA in Susceptibility to Antibody-Mediated Complement-Dependent Killing and Virulence of Salmonella enterica Serovar Typhimurium
    Edna M. Ondari, Jennifer N. Heath, Elizabeth J. Klemm, Gemma Langridge, Lars Barquist, David A. Goulding, Simon Clare, Gordon Dougan, Robert A. Kingsley, Calman A. MacLennan
  • Open Access
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    SipA Activation of Caspase-3 Is a Decisive Mediator of Host Cell Survival at Early Stages of Salmonella enterica Serovar Typhimurium Infection
    Anne McIntosh, Lynsey M. Meikle, Michael J. Ormsby, Beth A. McCormick, John M. Christie, James M. Brewer, Mark Roberts, Daniel M. Wall

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