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Infection and Immunity
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Serum

  • (p)ppGpp-Dependent Regulation of the Nucleotide Hydrolase PpnN Confers Complement Resistance in <span class="named-content genus-species" id="named-content-1">Salmonella enterica</span> Serovar Typhimurium
    Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    (p)ppGpp-Dependent Regulation of the Nucleotide Hydrolase PpnN Confers Complement Resistance in Salmonella enterica Serovar Typhimurium

    The stringent response is an essential mechanism of metabolic reprogramming during environmental stress that is mediated by the nucleotide alarmones guanosine tetraphosphate and pentaphosphate [(p)ppGpp]. In addition to physiological adaptations, (p)ppGpp also regulates virulence programs in pathogenic bacteria, including Salmonella enterica serovar Typhimurium. S...

    N. Y Elizabeth Chau, Deyanira Pérez-Morales, Wael Elhenawy, Víctor H. Bustamante, Yong E. Zhang, Brian K. Coombes
  • Bacterial Infections
    Contribution of Streptococcus mutans Strains with Collagen-Binding Proteins in the Presence of Serum to the Pathogenesis of Infective Endocarditis
    Masatoshi Otsugu, Ryota Nomura, Saaya Matayoshi, Noboru Teramoto, Kazuhiko Nakano
  • Microbial Immunity and Vaccines
    Use of Moraxella catarrhalis Lipooligosaccharide Mutants To Identify Specific Oligosaccharide Epitopes Recognized by Human Serum Antibodies
    Johanna M. Schwingel, Katie J. Edwards, Andrew D. Cox, Hussein Masoud, James C. Richards, Frank St. Michael, Carmen D. Tekwe, Sanjay Sethi, Timothy F. Murphy, Anthony A. Campagnari
  • Molecular Pathogenesis
    Human Serum Induces Streptococcal C5a Peptidase Expression
    Ute Gleich-Theurer, Simone Aymanns, Gregor Haas, Stefanie Mauerer, Julia Vogt, Barbara Spellerberg
  • Molecular Pathogenesis
    Factor H-Binding Protein Is Important for Meningococcal Survival in Human Whole Blood and Serum and in the Presence of the Antimicrobial Peptide LL-37
    K. L. Seib, D. Serruto, F. Oriente, I. Delany, J. Adu-Bobie, D. Veggi, B. Aricò, R. Rappuoli, M. Pizza
  • Molecular Pathogenesis
    Heptose I Glycan Substitutions on Neisseria gonorrhoeae Lipooligosaccharide Influence C4b-Binding Protein Binding and Serum Resistance
    Sanjay Ram, Jutamas Ngampasutadol, Andrew D. Cox, Anna M. Blom, Lisa A. Lewis, Frank St. Michael, Jacek Stupak, Sunita Gulati, Peter A. Rice
  • Molecular Pathogenesis
    Extracellular Gelatinase of Enterococcus faecalis Destroys a Defense System in Insect Hemolymph and Human Serum
    Shin Yong Park, Kyoung Mi Kim, Joon Ha Lee, Sook Jae Seo, In Hee Lee
  • Molecular Pathogenesis
    Identification of a Novel Virulence Determinant with Serum Opacification Activity in Streptococcus suis
    Christoph G. Baums, Ute Kaim, Marcus Fulde, Girish Ramachandran, Ralph Goethe, Peter Valentin-Weigand
  • Molecular Pathogenesis
    Intraspecies and Temperature-Dependent Variations in Susceptibility of Yersinia pestis to the Bactericidal Action of Serum and to Polymyxin B
    Andrey P. Anisimov, Svetlana V. Dentovskaya, Galina M. Titareva, Irina V. Bakhteeva, Rima Z. Shaikhutdinova, Sergey V. Balakhonov, Buko Lindner, Nina A. Kocharova, Sof'ya N. Senchenkova, Otto Holst, Gerald B. Pier, Yuriy A. Knirel
  • Fungal and Parasitic Infections
    Calcineurin Is Required for Candida albicans To Survive Calcium Stress in Serum
    Jill R. Blankenship, Joseph Heitman

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