Shiga Toxin 2

Molecular Pathogenesis | Spotlight
Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide
Steven D. Zumbrun, Leanne Hanson, James F. Sinclair, James Freedy, Angela R. Melton-Celsa, Jaime Rodriguez-Canales, Jeffrey C. Hanson, Alison D. O'Brien
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Shiga Toxin 2 and Flagellin from Shiga-Toxigenic Escherichia coli Superinduce Interleukin-8 through Synergistic Effects on Host Stress-Activated Protein Kinase Activation
Dakshina M. Jandhyala, Trisha J. Rogers, Anne Kane, Adrienne W. Paton, James C. Paton, Cheleste M. Thorpe
Host Response and Inflammation
Distinct Physiologic and Inflammatory Responses Elicited in Baboons after Challenge with Shiga Toxin Type 1 or 2 from Enterohemorrhagic Escherichia coli
D. J. Stearns-Kurosawa, Valta Collins, Scott Freeman, Vernon L. Tesh, Shinichiro Kurosawa
Microbial Immunity and Vaccines
Evaluation of Fab and F(ab′)₂ Fragments and Isotype Variants of a Recombinant Human Monoclonal Antibody against Shiga Toxin 2
Donna E. Akiyoshi, Abhineet S. Sheoran, Curtis M. Rich, L. Richard, Susan Chapman-Bonofiglio, Saul Tzipori
Microbial Immunity and Vaccines
An Orally Applicable Shiga Toxin Neutralizer Functions in the Intestine To Inhibit the Intracellular Transport of the Toxin
Miho Watanabe-Takahashi, Toshio Sato, Taeko Dohi, Noriko Noguchi, Fumi Kano, Masayuki Murata, Takashi Hamabata, Yasuhiro Natori, Kiyotaka Nishikawa
Molecular Pathogenesis
Monoclonal Antibody 11E10, Which Neutralizes Shiga Toxin Type 2 (Stx2), Recognizes Three Regions on the Stx2 A Subunit, Blocks the Enzymatic Action of the Toxin In Vitro, and Alters the Overall Cellular Distribution of the Toxin
Michael J. Smith, Angela R. Melton-Celsa, James F. Sinclair, Humberto M. Carvalho, Cory M. Robinson, Alison D. O'Brien
Molecular Pathogenesis
Shiga Toxin 2 Is Specifically Released from Bacterial Cells by Two Different Mechanisms
Takeshi Shimizu, Yuko Ohta, Masatoshi Noda
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Shiga Toxin 2 Targets the Murine Renal Collecting Duct Epithelium
Mitchell A. Psotka, Fumiko Obata, Glynis L. Kolling, Lisa K. Gross, Moin A. Saleem, Simon C. Satchell, Peter W. Mathieson, Tom G. Obrig
Bacterial Infections | Spotlight
Human Microbiota-Secreted Factors Inhibit Shiga Toxin Synthesis by Enterohemorrhagic Escherichia coli O157:H7
Thibaut de Sablet, Christophe Chassard, Annick Bernalier-Donadille, Marjolaine Vareille, Alain P. Gobert, Christine Martin
Molecular Pathogenesis
Bacteriophage 2851 Is a Prototype Phage for Dissemination of the Shiga Toxin Variant Gene 2c in Escherichia coli O157:H7
Eckhard Strauch, Jens Andre Hammerl, Antje Konietzny, Susanne Schneiker-Bekel, Walter Arnold, Alexander Goesmann, Alfred Pühler, Lothar Beutin

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Shiga Toxin 2

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