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Streptococcus mutans

  • Contribution of Severe Dental Caries Induced by <span class="named-content genus-species" id="named-content-1">Streptococcus mutans</span> to the Pathogenicity of Infective Endocarditis
    Bacterial Infections
    Contribution of Severe Dental Caries Induced by Streptococcus mutans to the Pathogenicity of Infective Endocarditis

    Streptococcus mutans, a major pathogen of dental caries, is regarded as a causative agent of infective endocarditis (IE), which mainly occurs in patients with underlying heart disease. However, it remains unknown whether severe dental caries that extend to pulp space represent a possible route of infection. In the present study, we evaluated the virulence of...

    Ryota Nomura, Saaya Matayoshi, Masatoshi Otsugu, Takahiro Kitamura, Noboru Teramoto, Kazuhiko Nakano
  • Open Access
    Multi-omics Analyses Reveal Synergistic Carbohydrate Metabolism in <span class="named-content genus-species" id="named-content-1">Streptococcus mutans</span>-<span class="named-content genus-species" id="named-content-2">Candida albicans</span> Mixed-Species Biofilms
    Host-Associated Microbial Communities
    Multi-omics Analyses Reveal Synergistic Carbohydrate Metabolism in Streptococcus mutans-Candida albicans Mixed-Species Biofilms

    Candida albicans, a major opportunistic fungal pathogen, is frequently found together with Streptococcus mutans in dental biofilms associated with severe childhood caries (tooth decay), a prevalent pediatric oral disease. However, the impact of this cross-kingdom relationship on...

    K. Ellepola, T. Truong, Y. Liu, Q. Lin, T. K. Lim, Y. M. Lee, T. Cao, H. Koo, C. J. Seneviratne
  • Molecular Pathogenesis
    Glucan Binding Protein C of Streptococcus mutans Mediates both Sucrose-Independent and Sucrose-Dependent Adherence
    Joshua L. Mieher, Matthew R. Larson, Norbert Schormann, Sangeetha Purushotham, Ren Wu, Kanagalaghatta R. Rajashankar, Hui Wu, Champion Deivanayagam
  • Bacterial Infections
    Contribution of Streptococcus mutans Strains with Collagen-Binding Proteins in the Presence of Serum to the Pathogenesis of Infective Endocarditis
    Masatoshi Otsugu, Ryota Nomura, Saaya Matayoshi, Noboru Teramoto, Kazuhiko Nakano
  • Bacterial Infections
    AtlA Mediates Extracellular DNA Release, Which Contributes to Streptococcus mutans Biofilm Formation in an Experimental Rat Model of Infective Endocarditis
    Chiau-Jing Jung, Ron-Bin Hsu, Chia-Tung Shun, Chih-Chieh Hsu, Jean-San Chia
  • Molecular Pathogenesis
    The Streptococcus mutans Serine/Threonine Kinase, PknB, Regulates Competence Development, Bacteriocin Production, and Cell Wall Metabolism
    Liliana Danusia Banu, Georg Conrads, Hubert Rehrauer, Haitham Hussain, Elaine Allan, Jan R. van der Ploeg
  • Molecular Pathogenesis
    Characteristics of Biofilm Formation by Streptococcus mutans in the Presence of Saliva
    Sug-Joon Ahn, Sang-Joon Ahn, Zezhang T. Wen, L. Jeannine Brady, Robert A. Burne
  • Host Response and Inflammation
    Mutans Streptococcal Infection Induces Salivary Antibody to Virulence Proteins and Associated Functional Domains
    R. D. Nogueira, W. F. King, G. Gunda, S. Culshaw, M. A. Taubman, R. O. Mattos-Graner, D. J. Smith
  • Molecular Pathogenesis
    LiaS Regulates Virulence Factor Expression in Streptococcus mutans
    Patrick Chong, Laura Drake, Indranil Biswas
  • Molecular Pathogenesis
    Requirements for Surface Expression and Function of Adhesin P1 from Streptococcus mutans
    Paula J. Crowley, Trevor B. Seifert, Ryutaro Isoda, Marloes van Tilburg, Monika W. Oli, Rebekah A. Robinette, William P. McArthur, Arnold S. Bleiweis, L. Jeannine Brady

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