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Infection and Immunity
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Streptococcus pneumoniae

  • Bacterial Infections
    Cigarette Smoke Exposure Impairs Pulmonary Bacterial Clearance and Alveolar Macrophage Complement-Mediated Phagocytosis of Streptococcus pneumoniae
    John C. Phipps, David M. Aronoff, Jeffrey L. Curtis, Deepti Goel, Edmund O'Brien, Peter Mancuso
  • Microbial Immunity and Vaccines
    Immunization with a Combination of Three Pneumococcal Proteins Confers Additive and Broad Protection against Streptococcus pneumoniae Infections in Mice
    Kaifeng Wu, Xuemei Zhang, Jing Shi, Nan Li, Dairong Li, Miao Luo, Ju Cao, Nanlin Yin, Hong Wang, Wenchun Xu, Yujuan He, Yibing Yin
  • Bacterial Infections
    Enhanced Susceptibility to Acute Pneumococcal Otitis Media in Mice Deficient in Complement C1qa, Factor B, and Factor B/C2
    Hua Hua Tong, Yong Xing Li, Gregory L. Stahl, Joshua M. Thurman
  • Molecular Pathogenesis
    The Streptococcuspneumoniae Capsule Inhibits Complement Activity and Neutrophil Phagocytosis by Multiple Mechanisms
    Catherine Hyams, Emilie Camberlein, Jonathan M. Cohen, Katie Bax, Jeremy S. Brown
  • Molecular Pathogenesis
    Streptococcus pneumoniae Resistance to Complement-Mediated Immunity Is Dependent on the Capsular Serotype
    Catherine Hyams, Jose Yuste, Katie Bax, Emilie Camberlein, Jeffrey N. Weiser, Jeremy S. Brown
  • Host Response and Inflammation
    The Effects of PspC on Complement-Mediated Immunity to Streptococcus pneumoniae Vary with Strain Background and Capsular Serotype
    Jose Yuste, Suneeta Khandavilli, Naadir Ansari, Kairya Muttardi, Laura Ismail, C. Hyams, Jeffrey Weiser, Timothy Mitchell, Jeremy S. Brown
  • Molecular Pathogenesis
    Characterization of Novel β-Galactosidase Activity That Contributes to Glycoprotein Degradation and Virulence in Streptococcus pneumoniae
    Vanessa S. Terra, Karen A. Homer, Susmitha G. Rao, Peter W. Andrew, Hasan Yesilkaya
  • Molecular Pathogenesis
    Pyruvate Formate Lyase Is Required for Pneumococcal Fermentative Metabolism and Virulence
    Hasan Yesilkaya, Francesca Spissu, Sandra M. Carvalho, Vanessa S. Terra, Karen A. Homer, Rachel Benisty, Nurith Porat, Ana R. Neves, Peter W. Andrew
  • Microbial Immunity and Vaccines
    PspA Family Fusion Proteins Delivered by Attenuated Salmonella enterica Serovar Typhimurium Extend and Enhance Protection against Streptococcus pneumoniae
    Wei Xin, Yuhua Li, Hua Mo, Kenneth L. Roland, Roy Curtiss
  • Microbial Immunity and Vaccines
    Oligoclonal CD4+ T Cells Promote Host Memory Immune Responses to Zwitterionic Polysaccharide of Streptococcus pneumoniae
    Laura Groneck, David Schrama, Mario Fabri, Tom Li Stephen, Fabian Harms, Sonja Meemboor, Helena Hafke, Martina Bessler, Jürgen C. Becker, Wiltrud M. Kalka-Moll

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