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Infection and Immunity
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Streptolysins

  • Molecular Pathogenesis
    Requirement and Synergistic Contribution of Platelet-Activating Factor Acetylhydrolase Sse and Streptolysin S to Inhibition of Neutrophil Recruitment and Systemic Infection by Hypervirulent emm3 Group A Streptococcus in Subcutaneous Infection of Mice
    Wenchao Feng, Dylan Minor, Mengyao Liu, Benfang Lei
  • Bacterial Infections
    Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae
    Rendong Fang, Rui Wu, Huihui Du, Meilan Jin, Yajing Liu, Guihua Lei, Bing Jiang, Zehui Lei, Yuanyi Peng, Kui Nie, Kohsuke Tsuchiya
  • Microbial Immunity and Vaccines
    Immunization with a Combination of Three Pneumococcal Proteins Confers Additive and Broad Protection against Streptococcus pneumoniae Infections in Mice
    Kaifeng Wu, Xuemei Zhang, Jing Shi, Nan Li, Dairong Li, Miao Luo, Ju Cao, Nanlin Yin, Hong Wang, Wenchun Xu, Yujuan He, Yibing Yin
  • Molecular Pathogenesis
    Human α-Defensins Inhibit Hemolysis Mediated by Cholesterol-Dependent Cytolysins
    Robert I. Lehrer, Grace Jung, Piotr Ruchala, Wei Wang, Ewa D. Micewicz, Alan J. Waring, Eugene J. Gillespie, Kenneth A. Bradley, Adam J. Ratner, Richard F. Rest, Wuyuan Lu
  • Host Response and Inflammation
    Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils
    Anna Martner, Claes Dahlgren, James C. Paton, Agnes E. Wold
  • Molecular Pathogenesis
    CcpA-Mediated Repression of Streptolysin S Expression and Virulence in the Group A Streptococcus
    Traci L. Kinkel, Kevin S. McIver
  • Host Response and Inflammation
    Critical Involvement of Pneumolysin in Production of Interleukin-1α and Caspase-1-Dependent Cytokines in Infection with Streptococcus pneumoniae In Vitro: a Novel Function of Pneumolysin in Caspase-1 Activation
    Shereen Shoma, Kohsuke Tsuchiya, Ikuo Kawamura, Takamasa Nomura, Hideki Hara, Ryosuke Uchiyama, Sylvia Daim, Masao Mitsuyama
  • Molecular Pathogenesis
    Role for sagA and siaA in Quorum Sensing and Iron Regulation in Streptococcus pyogenes
    Kowthar Y. Salim, Joyce C. de Azavedo, Darrin J. Bast, Dennis G. Cvitkovitch
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Pneumolysin Causes Neuronal Cell Death through Mitochondrial Damage
    Johann S. Braun, Olaf Hoffmann, Miriam Schickhaus, Dorette Freyer, Emilie Dagand, Daniela Bermpohl, Tim J. Mitchell, Ingo Bechmann, Joerg R. Weber
  • Molecular Pathogenesis
    Pneumolysin, PspA, and PspC Contribute to Pneumococcal Evasion of Early Innate Immune Responses during Bacteremia in Mice
    Lisa R. Quin, Quincy C. Moore, Larry S. McDaniel

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