Streptolysins

Molecular Pathogenesis
Requirement and Synergistic Contribution of Platelet-Activating Factor Acetylhydrolase Sse and Streptolysin S to Inhibition of Neutrophil Recruitment and Systemic Infection by Hypervirulent emm3 Group A Streptococcus in Subcutaneous Infection of Mice
Wenchao Feng, Dylan Minor, Mengyao Liu, Benfang Lei
Bacterial Infections
Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae
Rendong Fang, Rui Wu, Huihui Du, Meilan Jin, Yajing Liu, Guihua Lei, Bing Jiang, Zehui Lei, Yuanyi Peng, Kui Nie, Kohsuke Tsuchiya
Microbial Immunity and Vaccines
Immunization with a Combination of Three Pneumococcal Proteins Confers Additive and Broad Protection against Streptococcus pneumoniae Infections in Mice
Kaifeng Wu, Xuemei Zhang, Jing Shi, Nan Li, Dairong Li, Miao Luo, Ju Cao, Nanlin Yin, Hong Wang, Wenchun Xu, Yujuan He, Yibing Yin
Molecular Pathogenesis
Human α-Defensins Inhibit Hemolysis Mediated by Cholesterol-Dependent Cytolysins
Robert I. Lehrer, Grace Jung, Piotr Ruchala, Wei Wang, Ewa D. Micewicz, Alan J. Waring, Eugene J. Gillespie, Kenneth A. Bradley, Adam J. Ratner, Richard F. Rest, Wuyuan Lu
Host Response and Inflammation
Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils
Anna Martner, Claes Dahlgren, James C. Paton, Agnes E. Wold
Molecular Pathogenesis
CcpA-Mediated Repression of Streptolysin S Expression and Virulence in the Group A Streptococcus
Traci L. Kinkel, Kevin S. McIver
Host Response and Inflammation
Critical Involvement of Pneumolysin in Production of Interleukin-1α and Caspase-1-Dependent Cytokines in Infection with Streptococcus pneumoniae In Vitro: a Novel Function of Pneumolysin in Caspase-1 Activation
Shereen Shoma, Kohsuke Tsuchiya, Ikuo Kawamura, Takamasa Nomura, Hideki Hara, Ryosuke Uchiyama, Sylvia Daim, Masao Mitsuyama
Molecular Pathogenesis
Role for sagA and siaA in Quorum Sensing and Iron Regulation in Streptococcus pyogenes
Kowthar Y. Salim, Joyce C. de Azavedo, Darrin J. Bast, Dennis G. Cvitkovitch
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Pneumolysin Causes Neuronal Cell Death through Mitochondrial Damage
Johann S. Braun, Olaf Hoffmann, Miriam Schickhaus, Dorette Freyer, Emilie Dagand, Daniela Bermpohl, Tim J. Mitchell, Ingo Bechmann, Joerg R. Weber
Molecular Pathogenesis
Pneumolysin, PspA, and PspC Contribute to Pneumococcal Evasion of Early Innate Immune Responses during Bacteremia in Mice
Lisa R. Quin, Quincy C. Moore, Larry S. McDaniel

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