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Infection and Immunity
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tuberculosis vaccines

  • Microbial Immunity and Vaccines
    Identification of Mycobacterial Ribosomal Proteins as Targets for CD4+ T Cells That Enhance Protective Immunity in Tuberculosis

    Mycobacterium tuberculosis remains a threat to global health, and a more efficacious vaccine is needed to prevent disease caused by M. tuberculosis. We previously reported that the mycobacterial ribosome is a major target of CD4+ T cells in mice immunized with a genetically modified...

    Steven C. Kennedy, Alison J. Johnson, Sushma Bharrhan, Cecilia S. Lindestam Arlehamn, Jiayong Xu, Scott J. Garforth, John Chan, William R. Jacobs, Alessandro Sette, Steven C. Almo, Steven A. Porcelli
  • Open Access
    Microbial Immunity and Vaccines
    Antigen Localization Influences the Magnitude and Kinetics of Endogenous Adaptive Immune Response to Recombinant Salmonella Vaccines
    Yanina R. Sevastsyanovich, David R. Withers, Claire L. Marriott, Faye C. Morris, Timothy J. Wells, Douglas F. Browning, Irene Beriotto, Ewan Ross, Hossam Omar Ali, Catherine A. Wardius, Adam F. Cunningham, Ian R. Henderson, Amanda E. Rossiter
  • Host Response and Inflammation
    Mycobacterium tuberculosis Culture Filtrate Proteins plus CpG Oligodeoxynucleotides Confer Protection to Mycobacterium bovis BCG-Primed Mice by Inhibiting Interleukin-4 Secretion
    Denise Morais da Fonseca, Celio Lopes Silva, Pryscilla Fanini Wowk, Marina Oliveira e Paula, Simone Gusmão Ramos, Cynthia Horn, Gilles Marchal, Vânia Luiza Deperon Bonato
  • Microbial Immunity and Vaccines
    Viral Booster Vaccines Improve Mycobacterium bovis BCG-Induced Protection against Bovine Tuberculosis
    H. Martin Vordermeier, Bernardo Villarreal-Ramos, Paul J. Cockle, Martin McAulay, Shelley G. Rhodes, Tyler Thacker, Sarah C. Gilbert, Helen McShane, Adrian V. S. Hill, Zhou Xing, R. Glyn Hewinson
  • Host Response and Inflammation
    Vaccine-Elicited 10-Kilodalton Culture Filtrate Protein-Specific CD8+ T Cells Are Sufficient To Mediate Protection against Mycobacterium tuberculosis Infection
    Ying Wu, Joshua S. Woodworth, Daniel S. Shin, Sheldon Morris, Samuel M. Behar
  • Microbial Immunity and Vaccines
    DNA Polymorphisms in the pepA and PPE18 Genes among Clinical Strains of Mycobacterium tuberculosis: Implications for Vaccine Efficacy
    Andrea M. Hebert, Sarah Talarico, Dong Yang, Riza Durmaz, Carl F. Marrs, Lixin Zhang, Betsy Foxman, Zhenhua Yang
  • Microbial Immunity and Vaccines
    Effects of DNA- and Mycobacterium bovis BCG-Based Delivery of the Flt3 Ligand on Protective Immunity to Mycobacterium tuberculosis
    James A. Triccas, Elena Shklovskaya, Joanne Spratt, Anthony A. Ryan, Umaimainthan Palendira, Barbara Fazekas de StGroth, Warwick J. Britton
  • Microbial Immunity and Vaccines | Spotlight
    Protective Immune Responses to a Recombinant Adenovirus Type 35 Tuberculosis Vaccine in Two Mouse Strains: CD4 and CD8 T-Cell Epitope Mapping and Role of Gamma Interferon
    Katarina Radošević, Catharina W. Wieland, Ariane Rodriguez, Gerrit Jan Weverling, Ratna Mintardjo, Gert Gillissen, Ronald Vogels, Yasir A. W. Skeiky, David M. Hone, Jerald C. Sadoff, Tom van der Poll, Menzo Havenga, Jaap Goudsmit
  • Bacterial Infections
    Is Interleukin-4δ3 Splice Variant Expression in Bovine Tuberculosis a Marker of Protective Immunity?
    Shelley G. Rhodes, Jason Sawyer, Adam O. Whelan, Gillian S. Dean, Michael Coad, Katie J. Ewer, Andreas S. Waldvogel, Anthony Zakher, Derek J. Clifford, R. Glyn Hewinson, H. Martin Vordermeier
  • Host Response and Inflammation
    Immunogenicity of Eight Dormancy Regulon-Encoded Proteins of Mycobacterium tuberculosis in DNA-Vaccinated and Tuberculosis-Infected Mice
    Virginie Roupie, Marta Romano, Lei Zhang, Hannelie Korf, May Young Lin, Kees L. M. C. Franken, Tom H. M. Ottenhoff, Michèl R. Klein, Kris Huygen

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